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Skincare Ingredient

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Caprylyl Glycol

In Skincare: Is Caprylyl Glycol Safe? Comedogenic Rating & Side Effects

Comedogenicity (pore clogging)
1/5 — Very low risk
Safety (overall safety)
2/5 — Low risk
Irritancy (skin irritation)
2/5 — Low risk

Safety Information

Caprylyl Glycol is generally recognized as safe for use in cosmetics by the Cosmetic Ingredient Review (CIR) Expert Panel and is classified as a low hazard ingredient by the Environmental Working Group (EWG). It may cause mild irritation or stinging in individuals with sensitive skin or when used at higher concentrations. While it is not typically comedogenic, it should be used with caution in formulations intended for acne-prone skin.

Quick Insights

At a glance

  • 01

    Caprylyl glycol functions as a skin and hair conditioning agent.

  • 02

    This ingredient can be obtained through synthetic or naturally derived processes.

  • 03

    Caprylyl glycol contributes to formula preservation by inhibiting microbial growth.

  • 04

    The CIR Expert Panel has determined caprylyl glycol to be safe for use in cosmetic formulations.

Overview

Ingredient Profile

Caprylyl glycol is a versatile ingredient that functions as both a humectant, drawing moisture to the skin, and an emollient, helping to soften and smooth. It can be derived from plant sources like coconut or produced synthetically and contributes to the texture and stability of skincare formulations. Research suggests it may also possess mild antibacterial properties, potentially supporting preservative systems in leave-on products. Safety assessments indicate caprylyl glycol is non-irritating and safe for use in cosmetics at concentrations up to 5%.
Classifications
Preservative
Plant Extracts

Data & Research

Scientific Facts

Pentylene Glycol, 1,2-Hexanediol, and Caprylyl Glycol are water-soluble, with solubility increasing as the carbon chain length decreases. Caprylyl Glycol and Pentylene Glycol have been reported to exhibit some antimicrobial activity, which can be beneficial when used in conjunction with other preservatives.

Common Uses

Formulation in Caprylyl Glycol

Pentylene Glycol, 1,2-Hexanediol, and Caprylyl Glycol are commonly used in a variety of cosmetic products including baby care items, bath products, eye makeup, cleansing formulations, skin care products, and hair care products. They can function as a conditioning agent for hair. Additionally, these ingredients may enhance the effectiveness of other preservatives used in formulations.

Role of Caprylyl Glycol

Active Cosmetic Mechanisms

DEODORANT

Odor Neutralizer

Masks or neutralizes body odor

SCIENTIFIC ANALYSIS

// Evidence: Deodorants combat body odor through antimicrobial action against odor-causing bacteria (Corynebacterium, Staphylococcus), odor absorption/adsorption, enzymatic inhibition, or masking with fragrance. Active ingredients include antimicrobials, odor absorbers (zinc ricinoleate, cyclodextrins), and fragrances. They prevent bacterial conversion of sweat components into volatile malodorous compounds without reducing sweat volume.

HAIR CONDITIONING

Hair Softener

Improves hair manageability, softness, and appearance

SCIENTIFIC ANALYSIS

// Evidence: Hair conditioning ingredients smooth the cuticle, reduce frizz, and add shine through cationic surfactants (behentrimonium chloride), silicones (dimethicone, amodimethicone), natural oils, and proteins. These deposit on negatively charged damaged sites, neutralizing charge, filling surface irregularities, and providing lubrication. Mechanism involves electrostatic attraction, film formation, and surface smoothing.

SKIN CONDITIONING

Skin Enhancer

Maintains skin in good condition and improves its feel

SCIENTIFIC ANALYSIS

// Evidence: Skin conditioning ingredients enhance appearance, texture, and health of skin through various mechanisms. This broad category encompasses emollients, humectants, occlusives, and other agents that improve skin feel, appearance, and function. May work by moisturizing, smoothing, softening, or protecting skin. Effects include improved tactile properties, enhanced barrier function, and better overall skin condition.

SKIN CONDITIONING - EMOLLIENT

Skin Softener

Softens and smooths skin by filling gaps between cells

SCIENTIFIC ANALYSIS

// Evidence: Emollient ingredients create smooth, soft skin by filling spaces between corneocytes in stratum corneum. These include esters (isopropyl palmitate), oils (jojoba, argan), fatty alcohols, and silicones. The mechanism involves spreading on skin surface, filling microscopic irregularities, and creating lubricious film. Effects are immediate tactile improvement and visual smoothing. Emolliency measured by spreading coefficient and skin feel assessments.

Products

containing Caprylyl Glycol

22892 formulations
Liftactiv Supreme
Liftactiv Supreme
Vichy · moisturizer
Pure & Free Baby Sunscreen Stick SPF 50
Pure & Free Baby Sunscreen Stick SPF 50
Neutrogena · sunscreen
Sunflower Airy Sun Stick SPF 50+ PA++++
Sunflower Airy Sun Stick SPF 50+ PA++++
Skinfood · sunscreen

References

Scientific sources

[1]

Cosmeticsinfo.org, Accessed April 2024, ePublication

[2]

Scientific Reports, April 2021, Volume 11, Issue 1, article 8,695

[3]

International Journal of Cosmetic Science, October 2016, pages 496-503 and June 2009, pages 163-75

[4]

International Journal of Toxicology, September-October 2012, pages 147-168

[5]

Cutaneous and Ocular Toxicology, March 2009, Volume 28, pages 23-24

Semantic Analysis

Similar Ingredients

Ingredients with similar chemical profiles and skincare properties.

Frequently Asked Questions

Caprylyl Glycol — common questions

What is Caprylyl Glycol in skincare?

Caprylyl Glycol is a 1,2-glycol compound. It’s a family of ingredients including Pentylene Glycol (with 5 carbons), 1,2-Hexanediol (with 6 carbons), and Caprylyl Glycol (with 8 carbons). All of these compounds contain hydroxyl groups (-OH) on the first and second carbon atoms in their chain.

What does Caprylyl Glycol do? / Functions of Caprylyl Glycol?

Common functions: DEODORANT, HAIR CONDITIONING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT.

What is the comedogenic rating of Caprylyl Glycol? / Is Caprylyl Glycol comedogenic?
1 1/5 — Very low risk

Caprylyl Glycol has a comedogenic rating of 1 out of 5. A rating of 1 means it is unlikely to clog pores.

Does it clog pores?
Unlikely to Clog Pores

Caprylyl Glycol is unlikely to clog pores (rating 1/5).

Is Caprylyl Glycol safe for skin?
2 2/5 — Low risk

Caprylyl Glycol has a safety rating of 2 out of 5. A rating of 2 means it is generally considered safe for most skin types. Note: Caprylyl Glycol is generally recognized as safe for use in cosmetics by the Cosmetic Ingredient Review (CIR) Expert Panel and is classified as a low hazard ingredient by the Environmental Working Grou

Is Caprylyl Glycol good for sensitive skin?
2 2/5 — Low risk

Caprylyl Glycol has an irritancy rating of 2 out of 5. A rating of 2 means it is generally well-tolerated.

What are the side effects of Caprylyl Glycol in skincare?

Known considerations: Caprylyl Glycol is generally recognized as safe for use in cosmetics by the Cosmetic Ingredient Review (CIR) Expert Panel and is classified as a low hazard ingredient by the Environmental Working Group (EWG). It may cause mild irritation or stinging in individuals with sensitive skin or when used at higher concentrations. While it is not typically comedogenic, it should be used with caution in formulations intended for acne-prone skin.

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