SkinWis
SkinWis Scientific

Skincare Ingredient

Sign in to save this ingredient

Save ingredients to your skin profile and we'll use them when you look up products — instantly flagging what's reactive, neutral, or works well for your skin.

Glucose

In Skincare: Is Glucose Safe? Comedogenic Rating & Side Effects

Comedogenicity (pore clogging)
1/5 — Very low risk
Safety (overall safety)
1/5 — Very low risk
Irritancy (skin irritation)
1/5 — Very low risk

Safety Information

Common humectant/sugar; CIR and safety assessments indicate low irritation/sensitization and very low overall risk in cosmetics. The Cosmetic Ingredient Review Expert Panel has evaluated glucose and concluded it is safe for use in cosmetic products under normal, intended conditions.

Quick Insights

At a glance

  • 01

    Glucose, a plant-derived sugar, functions as a humectant to help draw moisture to the skin.

  • 02

    Glucose is utilized in lip balms and facial cleansers as a flavoring agent.

  • 03

    As a prebiotic, glucose supports the skin’s microbiome by nourishing beneficial microorganisms.

  • 04

    Glucose is also known as dextrose.

Key Benefits

What Glucose does for your skin

1 benefits
Hydration

Overview

Ingredient Profile

Glucose is a naturally occurring sugar that functions as a humectant, attracting and binding moisture to the skin. It can also contribute to the texture and flavor of cosmetic formulations like lip products and cleansers, and serves as a prebiotic that supports a balanced skin microbiome. Studies suggest that glucose may help reduce the appearance of discolorations by being metabolized into lactic acid, though leave-on exfoliants containing lactic acid may offer more pronounced results. Glucose is a safe ingredient for cosmetic use, typically supplied as an odorless white powder.
Classifications
Humectant
Prebiotic/Probiotic/Postbiotic

Data & Research

Scientific Facts

Glucose is commercially produced through the breakdown of starch using enzymes. Starch can be derived from various plants, including corn, rice, wheat, potato, cassava, arrowroot, and sago. Corn starch is the most frequently used source in the United States.

Common Uses

Formulation in Glucose

In cosmetics, glucose is utilized as a humectant (to draw moisture to the skin) and as a skin-conditioning agent. It may also be used as a flavoring agent in certain formulations.

Role of Glucose

Active Cosmetic Mechanisms

HUMECTANT

Moisture Magnet

Attracts and retains moisture in skin and hair

SCIENTIFIC ANALYSIS

// Evidence: Humectant ingredients draw water from the environment and deeper skin layers through hygroscopic properties. Common humectants include glycerin, propylene glycol, hyaluronic acid, urea, and alpha-hydroxy acids. These contain multiple hydroxyl groups or other hydrophilic functional groups that form hydrogen bonds with water molecules. Mechanism involves attracting water to the stratum corneum, reducing transepidermal water loss, and increasing skin hydration.

Products

containing Glucose

3865 formulations
Sun Mate Airy Sun Milk SPF 50+ / PA++++
Sun Mate Airy Sun Milk SPF 50+ / PA++++
Hera · sunscreen
Crema Idratante Purificante
Crema Idratante Purificante
Cera di Cupra · moisturizer
All-Around Safe Block Essence Sun Milk EX SPF 50+ PA++++
All-Around Safe Block Essence Sun Milk EX SPF 50+ PA++++
Missha · sunscreen

References

Scientific sources

[1]

International Journal of Molecular Sciences, March 2020, pages 1–13

[2]

Foods, March 2019, pages 1–27

[3]

Nature Medicine, May 2018, pages 617–627

[4]

Clinical Chemistry and Laboratory Medicine, September 2003, pages 1,224–1,228

Semantic Analysis

Similar Ingredients

Ingredients with similar chemical profiles and skincare properties.

Frequently Asked Questions

Glucose — common questions

What is Glucose in skincare?

Glucose is a simple sugar naturally found in plants. It’s produced through photosynthesis and exists as a white solid or an aqueous solution.

What does Glucose do? / Functions of Glucose?

Common functions: HUMECTANT.

What is the comedogenic rating of Glucose? / Is Glucose comedogenic?
1 1/5 — Very low risk

Glucose has a comedogenic rating of 1 out of 5. A rating of 1 means it is unlikely to clog pores.

Does it clog pores?
Unlikely to Clog Pores

Glucose is unlikely to clog pores (rating 1/5).

Is Glucose safe for skin?
1 1/5 — Very low risk

Glucose has a safety rating of 1 out of 5. A rating of 1 means it is generally considered safe for most skin types. Note: Common humectant/sugar; CIR and safety assessments indicate low irritation/sensitization and very low overall risk in cosmetics. The Cosmetic Ingredient Review Expert Panel has evaluated glucose and c

Is Glucose good for sensitive skin?
1 1/5 — Very low risk

Glucose has an irritancy rating of 1 out of 5. A rating of 1 means it is generally well-tolerated.

What are the side effects of Glucose in skincare?

Known considerations: Common humectant/sugar; CIR and safety assessments indicate low irritation/sensitization and very low overall risk in cosmetics. The Cosmetic Ingredient Review Expert Panel has evaluated glucose and concluded it is safe for use in cosmetic products under normal, intended conditions.

)