Skincare Ingredient
Save ingredients to your skin profile and we'll use them when you look up products — instantly flagging what's reactive, neutral, or works well for your skin.
Glycerin
In Skincare: Is Glycerin Safe? Comedogenic Rating & Side Effects
Safety Information
Quick Insights
At a glance
- 01
Glycerin is a humectant naturally found in skin.
- 02
Glycerin helps the skin maintain its moisture balance by drawing water to it.
- 03
Glycerin contributes to a healthy appearance and feel of the skin.
Key Benefits
What Glycerin does for your skin
Overview
Ingredient Profile
Data & Research
Scientific Facts
Common Uses
Formulation in Glycerin
Role of Glycerin
Active Cosmetic Mechanisms
DENATURANT
Alcohol Treatment AgentMakes alcohol undrinkable in cosmetic products
SCIENTIFIC ANALYSIS
// Evidence: Denaturants are added to ethanol to render it unfit for consumption while maintaining cosmetic functionality. Common denaturants include denatonium benzoate (extremely bitter), diethyl phthalate, and tert-butyl alcohol. This allows manufacturers to use tax-free specially denatured alcohol. Denaturants must meet specific regulatory formulations with precise ratios.
FRAGRANCE
Scent ProviderAdds pleasant scent to cosmetic products
SCIENTIFIC ANALYSIS
// Evidence: Fragrance ingredients provide aromatic appeal through essential oils, aroma chemicals, and natural extracts. These volatile compounds interact with olfactory receptors creating scent perception. Fragrance design considers top notes (high volatility), middle notes (moderate volatility), and base notes (low volatility) for scent development over time. Must consider stability, allergen content, and regulatory compliance.
HAIR CONDITIONING
Hair SoftenerImproves hair manageability, softness, and appearance
SCIENTIFIC ANALYSIS
// Evidence: Hair conditioning ingredients smooth the cuticle, reduce frizz, and add shine through cationic surfactants (behentrimonium chloride), silicones (dimethicone, amodimethicone), natural oils, and proteins. These deposit on negatively charged damaged sites, neutralizing charge, filling surface irregularities, and providing lubrication. Mechanism involves electrostatic attraction, film formation, and surface smoothing.
HUMECTANT
Moisture MagnetAttracts and retains moisture in skin and hair
SCIENTIFIC ANALYSIS
// Evidence: Humectant ingredients draw water from the environment and deeper skin layers through hygroscopic properties. Common humectants include glycerin, propylene glycol, hyaluronic acid, urea, and alpha-hydroxy acids. These contain multiple hydroxyl groups or other hydrophilic functional groups that form hydrogen bonds with water molecules. Mechanism involves attracting water to the stratum corneum, reducing transepidermal water loss, and increasing skin hydration.
ORAL CARE
Dental Health AgentMaintains or improves oral hygiene and dental health
SCIENTIFIC ANALYSIS
// Evidence: Oral care ingredients support dental health through fluoride compounds (stannous fluoride, sodium fluoride for remineralization), antimicrobials (triclosan, CPC), abrasives (silica for cleaning), and desensitizing agents (potassium nitrate, strontium chloride). Mechanisms include strengthening enamel through fluorapatite formation, reducing bacteria, removing stains, and blocking dentinal tubules. Must meet specific efficacy and safety standards.
PERFUMING
Fragrance ProviderProvides fragrance to enhance product appeal
SCIENTIFIC ANALYSIS
// Evidence: Perfuming ingredients add pleasant scents through complex mixtures of natural essential oils, aroma chemicals, and synthetic compounds. These volatile molecules evaporate and interact with olfactory receptors. Perfume construction uses top notes (citrus, herbs - high volatility), middle notes (floral, spice - moderate volatility), and base notes (woods, musks - low volatility) creating evolving scent profile. Must consider stability, allergen declaration, and IFRA compliance.
SKIN CONDITIONING - HUMECTANT
Hydration BoosterDraws moisture into skin for hydration
SCIENTIFIC ANALYSIS
// Evidence: Humectant-type skin conditioners attract and bind water to increase skin hydration. Key ingredients include glycerin, hyaluronic acid, sodium PCA, urea, and propylene glycol. These hygroscopic molecules form hydrogen bonds with water from dermis and environment, increasing water content in stratum corneum. The mechanism involves osmotic gradient creation and water binding through hydrophilic functional groups. Results in plumping effect and improved skin flexibility.
SKIN PROTECTING
Defensive ShieldShields skin from external aggressors and damage
SCIENTIFIC ANALYSIS
// Evidence: Skin protecting ingredients defend against environmental stressors, irritants, and damage through barrier enhancement, antioxidant activity, anti-pollution effects, or physical barriers. Include dimethicone (barrier), allantoin (soothing protectant), zinc oxide (physical protectant), and film-formers. Mechanisms vary: forming protective films, neutralizing oxidative stress, chelating pollutants, strengthening barrier function. Used in protective creams, barrier treatments, and defensive skincare against urban pollution, extreme weather.
SOLVENT
Ingredient DissolverDissolves other ingredients to create uniform formulations
SCIENTIFIC ANALYSIS
// Evidence: Solvents dissolve, dilute, or disperse other ingredients creating homogeneous solutions. Water is universal solvent for hydrophilic ingredients. Organic solvents include ethanol (dissolves fragrances, some actives), propylene glycol, and glycerin. Selection based on polarity matching between solvent and solute. Mechanism involves disrupting intermolecular forces in solute and surrounding with solvent molecules. Critical for maintaining ingredient solubility and product stability.
VISCOSITY CONTROLLING
Thickness RegulatorAdjusts product thickness and flow properties
SCIENTIFIC ANALYSIS
// Evidence: Viscosity controlling ingredients modify product flow characteristics through thickening or thinning. Thickeners include natural gums (xanthan, guar), synthetic polymers (carbomers, acrylates), and inorganic thickeners (silica, clays). Mechanism varies: polymer chain entanglement, hydrogen bonding networks, particle association, or swelling. Rheology modifiers create desired texture, prevent separation, control application properties, and affect sensory perception. Can produce Newtonian (constant viscosity) or non-Newtonian (shear-thinning, thixotropic) flow behavior.
Products
containing Glycerin
One-step login · Made for your skin
Want analysis that actually fits your skin?
Sign in once — we'll remember your skin type and make every analysis more relevant for you. for free!
Joined by people who care about their skin
References
Scientific sources
Journal of Pharmaceutical Investigation, March 2021, pages 223-231
International Journal of Toxicology, November/December 2019, Volume 38, Supplement 3, pages 6S-22S
International Journal of Cosmetic Science, August 2016, ePublication
British Journal of Dermatology, July 2008, pages 23-34
Journal of Cosmetic Dermatology, June 2007, pages 75-82
Proceedings of the National Academy of Sciences, June 2003, pages 7,360-7,365
Similar Ingredients
Ingredients with similar chemical profiles and skincare properties.
Frequently Asked Questions
Glycerin — common questions
What is Glycerin in skincare?
Glycerin, also known as glycerol, is a naturally occurring alcohol compound found in animal, plant, and human tissues. It can be derived from natural sources like soybeans, cane sugar, or corn syrup, or produced synthetically.
What does Glycerin do? / Functions of Glycerin?
Common functions: DENATURANT, FRAGRANCE, HAIR CONDITIONING, HUMECTANT, ORAL CARE, PERFUMING.
What is the comedogenic rating of Glycerin? / Is Glycerin comedogenic?
Glycerin has a comedogenic rating of 1 out of 5. A rating of 1 means it is unlikely to clog pores.
Does it clog pores?
Glycerin is unlikely to clog pores (rating 1/5).
Is Glycerin safe for skin?
Glycerin has a safety rating of 1 out of 5. A rating of 1 means it is generally considered safe for most skin types. Note: Well-studied humectant; CIR and broad cosmetic use support very low irritation/sensitization and non-comedogenicity for most users. The Cosmetic Ingredient Review (CIR) Expert Panel has deemed glyceri
Is Glycerin good for sensitive skin?
Glycerin has an irritancy rating of 1 out of 5. A rating of 1 means it is generally well-tolerated.
What are the side effects of Glycerin in skincare?
Known considerations: Well-studied humectant; CIR and broad cosmetic use support very low irritation/sensitization and non-comedogenicity for most users. The Cosmetic Ingredient Review (CIR) Expert Panel has deemed glycerin safe for use in cosmetics, and it is generally recognized as safe (GRAS) by the FDA when used in personal care products.