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Skincare Ingredient

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Glycolic Acid

In Skincare: Is Glycolic Acid Safe? Comedogenic Rating & Side Effects

Comedogenicity (pore clogging)
1/5 — Very low risk
Safety (overall safety)
3/5 — Moderate risk
Irritancy (skin irritation)
4/5 — High risk

Safety Information

Glycolic acid is generally recognized as safe for topical use at concentrations up to 10% in cosmetics, according to the Cosmetic Ingredient Review (CIR) Expert Panel. However, it may cause irritation, especially in individuals with sensitive skin, and formulations with concentrations above 10% or lower pH levels may increase the risk of skin damage and photosensitivity.

Quick Insights

At a glance

  • 01

    Glycolic acid is the most extensively researched alpha hydroxy acid (AHA).

  • 02

    This ingredient helps to exfoliate and renew the skin's surface.

  • 03

    Glycolic acid visibly improves several signs of aging, according to its properties.

  • 04

    It significantly increases skin hydration by improving moisture retention.

  • 05

    Recent research suggests that glycolic acid may offer some protection against ultraviolet (UV) damage.

  • 06

    Glycolic acid has a long-established history of safe use in cosmetic formulations.

Key Benefits

What Glycolic Acid does for your skin

3 benefits
Anti-Aging
Evens Skin Tone
Smooths Bumpy Skin

Overview

Ingredient Profile

Glycolic acid is an alpha hydroxy acid (AHA) that can both hydrate the skin and, at concentrations of 5% or greater, exfoliate dead surface cells. This exfoliation helps improve the appearance of sun damage, uneven skin tone, and signs of aging like fine lines and wrinkles. Research indicates glycolic acid also boosts hydration by supporting the skin’s natural production of hyaluronic acid, and emerging studies suggest it may offer some protection against UV damage—though sunscreen remains essential.
Classifications
Exfoliant
Humectant
pH Adjuster/Stabilizer

Data & Research

Scientific Facts

Glycolic acid and lactic acid are alpha hydroxy acids (AHAs). They can be produced naturally or synthetically. Glycolic acid is typically derived from sugar cane, while lactic acid originates primarily from milk and has a historical use dating back to ancient times.

Common Uses

Formulation in Glycolic Acid

Glycolic acid and lactic acid, along with their salts and esters, are utilized in cosmetics and personal care products to improve the appearance and feel of skin. They are frequently incorporated into formulations designed to enhance skin texture and overall complexion.

Role of Glycolic Acid

Active Cosmetic Mechanisms

BUFFERING

pH Stabilizer

Maintains stable pH levels in products

SCIENTIFIC ANALYSIS

// Evidence: Buffering systems resist pH changes through weak acid-conjugate base pairs (citric acid/sodium citrate, lactic acid/sodium lactate, phosphate salts) that operate within specific pH ranges based on their pKa values. The mechanism follows the Henderson-Hasselbalch equation, with buffer components neutralizing added H⁺ or OH⁻ ions. Proper buffering prevents pH drift and maintains efficacy.

Products

containing Glycolic Acid

3616 formulations
Premium Brightening Facial Foam
Premium Brightening Facial Foam
Fairy Skin · cleanser
Microdermabrasion Renewing Age-Defying Face Exfoliator
Microdermabrasion Renewing Age-Defying Face Exfoliator
Dr. Brandt Skincare · exfoliators
ExfoliKate® Cleanser Daily Foaming Wash
ExfoliKate® Cleanser Daily Foaming Wash
Kate Somerville · cleanser

References

Scientific sources

[1]

Molecules, April 2018, 23(4), ePublication

[2]

DNA Cell Biology, February 2017, pages 177-187

[3]

Journal of Clinical and Aesthetic Dermatology, October 2015, pages 21-26

[4]

BioMed Research International, 2015, Volume 2015

[5]

Dermatology Research and Practice, February 2015, Volume 2015

Semantic Analysis

Similar Ingredients

Ingredients with similar chemical profiles and skincare properties.

Frequently Asked Questions

Glycolic Acid — common questions

What is Glycolic Acid in skincare?

Glycolic acid and lactic acid are both alpha hydroxy acids (AHAs). AHAs are naturally occurring organic acids, either produced synthetically or derived from sources like sugar cane (glycolic acid) and milk (lactic acid). Salts and esters of both glycolic and lactic acids are also frequently used in cosmetic formulations. These derivatives include ammonium glycolate, sodium glycolate, ammonium lactate, calcium lactate, potassium lactate, sodium lactate and TEA-lactate (all glycolic acid salts), a

What does Glycolic Acid do? / Functions of Glycolic Acid?

Common functions: BUFFERING.

What is the comedogenic rating of Glycolic Acid? / Is Glycolic Acid comedogenic?
1 1/5 — Very low risk

Glycolic Acid has a comedogenic rating of 1 out of 5. A rating of 1 means it is unlikely to clog pores.

Does it clog pores?
Unlikely to Clog Pores

Glycolic Acid is unlikely to clog pores (rating 1/5).

Is Glycolic Acid safe for skin?
3 3/5 — Moderate risk

Glycolic Acid has a safety rating of 3 out of 5. A rating of 3 indicates moderate safety considerations. Note: Glycolic acid is generally recognized as safe for topical use at concentrations up to 10% in cosmetics, according to the Cosmetic Ingredient Review (CIR) Expert Panel. However, it may cause irritation

Is Glycolic Acid good for sensitive skin?
4 4/5 — High risk

Glycolic Acid has an irritancy rating of 4 out of 5. A rating of 4 means it has high irritation potential.

What are the side effects of Glycolic Acid in skincare?

Known considerations: Glycolic acid is generally recognized as safe for topical use at concentrations up to 10% in cosmetics, according to the Cosmetic Ingredient Review (CIR) Expert Panel. However, it may cause irritation, especially in individuals with sensitive skin, and formulations with concentrations above 10% or lower pH levels may increase the risk of skin damage and photosensitivity. Additional risks: skin irritation (irritancy rating 4/5).

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