Skincare Ingredient
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Hexapeptide-18
In Skincare: Is Hexapeptide-18 Safe? Comedogenic Rating & Side Effects
Safety Information
Overview
Ingredient Profile
Role of Hexapeptide-18
Active Cosmetic Mechanisms
HAIR CONDITIONING
Hair SoftenerImproves hair manageability, softness, and appearance
SCIENTIFIC ANALYSIS
// Evidence: Hair conditioning ingredients smooth the cuticle, reduce frizz, and add shine through cationic surfactants (behentrimonium chloride), silicones (dimethicone, amodimethicone), natural oils, and proteins. These deposit on negatively charged damaged sites, neutralizing charge, filling surface irregularities, and providing lubrication. Mechanism involves electrostatic attraction, film formation, and surface smoothing.
SKIN CONDITIONING
Skin EnhancerMaintains skin in good condition and improves its feel
SCIENTIFIC ANALYSIS
// Evidence: Skin conditioning ingredients enhance appearance, texture, and health of skin through various mechanisms. This broad category encompasses emollients, humectants, occlusives, and other agents that improve skin feel, appearance, and function. May work by moisturizing, smoothing, softening, or protecting skin. Effects include improved tactile properties, enhanced barrier function, and better overall skin condition.
Products
containing Hexapeptide-18
Similar Ingredients
Ingredients with similar chemical profiles and skincare properties.
Frequently Asked Questions
Hexapeptide-18 — common questions
What is Hexapeptide-18 in skincare?
Hexapeptide-18 is the synthetic peptide consisting of tyrosine, alanine, glycine, phenylalanine, leucine and aspartic acid
What does Hexapeptide-18 do? / Functions of Hexapeptide-18?
Common functions: HAIR CONDITIONING, SKIN CONDITIONING.
What is the comedogenic rating of Hexapeptide-18? / Is Hexapeptide-18 comedogenic?
The comedogenic rating of Hexapeptide-18 has not been established in our database.
Does it clog pores?
Whether Hexapeptide-18 clogs pores depends on the formulation and concentration.
Is Hexapeptide-18 safe for skin?
Hexapeptide-18 has a safety rating of 2 out of 5. A rating of 2 means it is generally considered safe for most skin types. Note: Cosmetic peptides like Hexapeptide-18 are generally considered low risk at typical use levels; limited specific comedogenicity/irritancy data published—rare sensitization possible in reactive skin. Li
Is Hexapeptide-18 good for sensitive skin?
Hexapeptide-18 tolerance on sensitive skin varies by individual.
What are the side effects of Hexapeptide-18 in skincare?
Known considerations: Cosmetic peptides like Hexapeptide-18 are generally considered low risk at typical use levels; limited specific comedogenicity/irritancy data published—rare sensitization possible in reactive skin. Limited safety data available; no specific concerns identified in available toxicological profiles.