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Polygonum Cuspidatum Root Extract

In Skincare: Is Polygonum Cuspidatum Root Extract Safe? Comedogenic Rating & Side Effects

Safety (overall safety)
2/5 — Low risk
Irritancy (skin irritation)
2/5 — Low risk

Safety Information

Plant extract rich in resveratrol and polyphenols. Limited safety data available, though resveratrol is generally considered safe for topical use; however, may cause mild irritation in some individuals.

Quick Insights

At a glance

  • 01

    Polygonum Cuspidatum Root Extract is an excellent source of the potent antioxidant resveratrol.

  • 02

    This extract helps inhibit the formation of substances that degrade collagen within skin.

  • 03

    Higher concentrations of Polygonum Cuspidatum Root Extract have been shown to visibly improve hyperpigmentation.

  • 04

    Polygonum Cuspidatum Root Extract can help reduce signs of skin irritation.

Key Benefits

What Polygonum Cuspidatum Root Extract does for your skin

2 benefits
Anti-Aging
Soothing

Overview

Ingredient Profile

Polygonum cuspidatum root extract, derived from Japanese knotweed, is a source of trans-resveratrol, a potent antioxidant considered readily absorbed by the skin. This extract helps protect against free radical damage and may reduce signs of irritation. Research suggests it can also inhibit the formation of advanced glycation end-products (AGEs), compounds that contribute to collagen breakdown and signs of aging. While higher concentrations (1% or more) have demonstrated hyperpigmentation-fading properties, lower levels offer antioxidant and soothing benefits.
Classifications
Antioxidant
Plant Extracts

Role of Polygonum Cuspidatum Root Extract

Active Cosmetic Mechanisms

ANTIOXIDANT

Anti-Aging Protector

Protects products and skin from oxidative damage and aging

SCIENTIFIC ANALYSIS

// Evidence: Antioxidants prevent or delay oxidation by donating electrons to free radicals, chelating pro-oxidant metals, or regenerating other antioxidants. Mechanisms include direct radical scavenging (vitamin E, vitamin C, BHT, BHA), metal chelation (EDTA), or enzymatic action. On skin, they neutralize reactive oxygen species (ROS) generated by UV radiation and pollution, preventing lipid peroxidation and DNA damage.

Products

containing Polygonum Cuspidatum Root Extract

911 formulations
Exfoliating Energy Scrub
Exfoliating Energy Scrub
Tom Ford · exfoliators
The Lifting and Firming Mask
The Lifting and Firming Mask
La Mer · masks
Genaissance de la Mer The Eye & Expression Cream
Genaissance de la Mer The Eye & Expression Cream
La Mer · eye-lip-care

References

Scientific sources

[1]

Evidence-Based Complementary and Alternative Medicine, April 2020, ePublication

[2]

Food and Science Nutrition, June 2019, pages 2,006-2,016

[3]

Biomedicines, September 2018, ePublication

[4]

Evidence Based Complementary and Alternative Medicine, September 2013, ePublication

[5]

International Journal of Preventive Medicine, April 2013, Supplement 1, pages S1-S4

[6]

Journal of Inflammation, February 2008, ePublication

Semantic Analysis

Similar Ingredients

Ingredients with similar chemical profiles and skincare properties.

Frequently Asked Questions

Polygonum Cuspidatum Root Extract — common questions

What is Polygonum Cuspidatum Root Extract in skincare?

Polygonum Cuspidatum Root Extract is an extract of the roots of the Japanese Knotweed, Polygonum cuspidatum, Polygonaceae

What does Polygonum Cuspidatum Root Extract do? / Functions of Polygonum Cuspidatum Root Extract?

Common functions: ANTIOXIDANT.

What is the comedogenic rating of Polygonum Cuspidatum Root Extract? / Is Polygonum Cuspidatum Root Extract comedogenic?

The comedogenic rating of Polygonum Cuspidatum Root Extract has not been established in our database.

Does it clog pores?
No Rating Available

Whether Polygonum Cuspidatum Root Extract clogs pores depends on the formulation and concentration.

Is Polygonum Cuspidatum Root Extract safe for skin?
2 2/5 — Low risk

Polygonum Cuspidatum Root Extract has a safety rating of 2 out of 5. A rating of 2 means it is generally considered safe for most skin types. Note: Plant extract rich in resveratrol and polyphenols. Limited safety data available, though resveratrol is generally considered safe for topical use; however, may cause mild irritation in some individual

Is Polygonum Cuspidatum Root Extract good for sensitive skin?
2 2/5 — Low risk

Polygonum Cuspidatum Root Extract has an irritancy rating of 2 out of 5. A rating of 2 means it is generally well-tolerated.

What are the side effects of Polygonum Cuspidatum Root Extract in skincare?

Known considerations: Plant extract rich in resveratrol and polyphenols. Limited safety data available, though resveratrol is generally considered safe for topical use; however, may cause mild irritation in some individuals.

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