Skincare Ingredient
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Retinol
In Skincare: Is Retinol Safe? Comedogenic Rating & Side Effects
Safety Information
Quick Insights
At a glance
- 01
Retinol is the common name for a molecule within the vitamin A family.
- 02
Research demonstrates retinol's efficacy in addressing signs of aging.
- 03
Retinol influences skin cell behavior and appearance to promote a more youthful complexion.
- 04
Retinol is available in various concentrations, allowing for use at different strengths.
Key Benefits
What Retinol does for your skin
Overview
Ingredient Profile
Data & Research
Scientific Facts
Common Uses
Formulation in Retinol
Role of Retinol
Active Cosmetic Mechanisms
SKIN CONDITIONING - MISCELLANEOUS
General Skin ImproverImproves skin condition through various mechanisms
SCIENTIFIC ANALYSIS
// Evidence: This category includes skin conditioning ingredients working through mechanisms not classified as emollient, humectant, or occlusive. May include antioxidants providing protective conditioning, peptides supporting structural proteins, botanical extracts with various bioactive effects, or ingredients that improve skin condition through multiple simultaneous mechanisms. Provides diverse skin benefits that dont fit into other specific subcategories.
Products
containing Retinol
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References
Scientific sources
Journal of Drugs in Dermatology, September 2019, pages 918-923; and March 2015, pages 271-280
Experimental Dermatology, August 2019, pages 906-913
Archives of Dermatological Research, May 2017, pages 275-283
International Journal of Cosmetic Science, February 2017, pages 56-65
Dermatology, May 2014, pages 314-325
Dermatoendocrinology, July 2012, issue 3, pages 308-319
Toxicological Research, March 2010, pages 61-66
Archives of Dermatology, May 2007, pages 606-612
The Journal of Pathology, January 2007, issue 2, pages 241-251
Clinical Interventions in Aging, December 2006, pages 327-348
Similar Ingredients
Ingredients with similar chemical profiles and skincare properties.
Frequently Asked Questions
Retinol — common questions
What is Retinol in skincare?
Retinol is a derivative of vitamin A widely used in dermatology for its scientifically proven effects on skin renewal and aging. In the skin, retinol is converted into retinaldehyde and then into retinoic acid, the biologically active form that binds to retinoic acid receptors in skin cells and regulates gene expression. This process increases epidermal cell turnover, helping to shed dead skin cells faster and promote the growth of new cells, which improves skin texture and unclogs pores. Retino
What does Retinol do? / Functions of Retinol?
Common functions: SKIN CONDITIONING - MISCELLANEOUS.
What is the comedogenic rating of Retinol? / Is Retinol comedogenic?
Retinol has a comedogenic rating of 1 out of 5. A rating of 1 means it is unlikely to clog pores.
Does it clog pores?
Retinol is unlikely to clog pores (rating 1/5).
Is Retinol safe for skin?
Retinol has a safety rating of 3 out of 5. A rating of 3 indicates moderate safety considerations. Note: Can cause irritation, particularly in higher concentrations or with overuse. The Cosmetic Ingredient Review (CIR) Expert Panel has noted that retinol may cause ocular and dermal irritation, and it is
Is Retinol good for sensitive skin?
Retinol has an irritancy rating of 4 out of 5. A rating of 4 means it has high irritation potential.
What are the side effects of Retinol in skincare?
Known considerations: Can cause irritation, particularly in higher concentrations or with overuse. The Cosmetic Ingredient Review (CIR) Expert Panel has noted that retinol may cause ocular and dermal irritation, and it is recommended to avoid use during pregnancy due to potential teratogenic effects and also can increase sun sensitivity. Retinol itself does not clog pores. It often helps prevent clogged pores because it increases cell turnover. Additional risks: skin irritation (irritancy rating 4/5).