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Skincare Ingredient

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Triethylhexanoin

In Skincare: Is Triethylhexanoin Safe? Comedogenic Rating & Side Effects

Comedogenicity (pore clogging)
1/5 — Very low risk
Safety (overall safety)
1/5 — Very low risk
Irritancy (skin irritation)
1/5 — Very low risk

Safety Information

CIR-reviewed ester emollient; low irritation/sensitization potential and no strong evidence of carcinogenicity or endocrine disruption at cosmetic use levels. It has a low comedogenic rating, indicating minimal likelihood of pore blockage, and is generally considered safe for use in cosmetics.

Quick Insights

At a glance

  • 01

    Triethylhexanoin is a synthetic mixture derived from glycerin and 2-ethylhexanoic acid.

  • 02

    This ingredient functions as a solvent and occlusive agent in cosmetic formulations.

  • 03

    Triethylhexanoin provides skin-conditioning emollient benefits and can also be used as a hair conditioner.

  • 04

    The CIR Expert Panel considers triethylhexanoin safe for use in cosmetics as currently practiced.

Key Benefits

What Triethylhexanoin does for your skin

1 benefits
Hydration

Overview

Ingredient Profile

Triethylhexanoin is a synthetic emollient and solvent composed of glycerin and 2-ethylhexanoic acid. It helps to soften skin, create a protective barrier, and improve the texture of hair when used in skincare and cosmetic formulations. Safety assessments indicate it is generally considered safe for topical use, typically found in concentrations between 3–5% in leave-on products and up to 63% in lipsticks.
Classifications
Solvent
Occlusive/Opacifying Agent
Humectant

Data & Research

Scientific Facts

Glyceryl triesters are produced through a chemical reaction between glycerin and fatty acids. This process creates esters – molecules formed when an alcohol (glycerin) reacts with a carboxylic acid (fatty acids). The specific fatty acid used determines the unique characteristics of each glyceryl triester, such as Trilaurin (derived from lauric acid) and Tristearin (derived from stearic acid).

Common Uses

Formulation in Triethylhexanoin

Glyceryl triesters are utilized for their various properties within cosmetic formulations. They function as hair conditioning agents, skin conditioning agents (both emollient and occlusive), and viscosity increasing agents. They are derived from natural sources like animal fats (tallow) and vegetable oils (palm-nut, coconut oil).

Role of Triethylhexanoin

Active Cosmetic Mechanisms

FRAGRANCE

Scent Provider

Adds pleasant scent to cosmetic products

SCIENTIFIC ANALYSIS

// Evidence: Fragrance ingredients provide aromatic appeal through essential oils, aroma chemicals, and natural extracts. These volatile compounds interact with olfactory receptors creating scent perception. Fragrance design considers top notes (high volatility), middle notes (moderate volatility), and base notes (low volatility) for scent development over time. Must consider stability, allergen content, and regulatory compliance.

HAIR CONDITIONING

Hair Softener

Improves hair manageability, softness, and appearance

SCIENTIFIC ANALYSIS

// Evidence: Hair conditioning ingredients smooth the cuticle, reduce frizz, and add shine through cationic surfactants (behentrimonium chloride), silicones (dimethicone, amodimethicone), natural oils, and proteins. These deposit on negatively charged damaged sites, neutralizing charge, filling surface irregularities, and providing lubrication. Mechanism involves electrostatic attraction, film formation, and surface smoothing.

PERFUMING

Fragrance Provider

Provides fragrance to enhance product appeal

SCIENTIFIC ANALYSIS

// Evidence: Perfuming ingredients add pleasant scents through complex mixtures of natural essential oils, aroma chemicals, and synthetic compounds. These volatile molecules evaporate and interact with olfactory receptors. Perfume construction uses top notes (citrus, herbs - high volatility), middle notes (floral, spice - moderate volatility), and base notes (woods, musks - low volatility) creating evolving scent profile. Must consider stability, allergen declaration, and IFRA compliance.

SKIN CONDITIONING

Skin Enhancer

Maintains skin in good condition and improves its feel

SCIENTIFIC ANALYSIS

// Evidence: Skin conditioning ingredients enhance appearance, texture, and health of skin through various mechanisms. This broad category encompasses emollients, humectants, occlusives, and other agents that improve skin feel, appearance, and function. May work by moisturizing, smoothing, softening, or protecting skin. Effects include improved tactile properties, enhanced barrier function, and better overall skin condition.

Products

containing Triethylhexanoin

1376 formulations
Clear Stick UV Protector WetForce Broad Spectrum Sunscreen SPF 50+
Clear Stick UV Protector WetForce Broad Spectrum Sunscreen SPF 50+
Shiseido · sunscreen
Enjoy Super Active Airy Sun Stick SPF 50+ PA++++
Enjoy Super Active Airy Sun Stick SPF 50+ PA++++
SCINIC · sunscreen
Enjoy All Round Airy Sun Stick SPF 50+ PA++++
Enjoy All Round Airy Sun Stick SPF 50+ PA++++
SCINIC · sunscreen

References

Scientific sources

[1]

CosmeticsInfo.org, Accessed November 2021, ePublication

[2]

Cosmetic Ingredient Review, February 2018, pages 1-40

Semantic Analysis

Similar Ingredients

Ingredients with similar chemical profiles and skincare properties.

Frequently Asked Questions

Triethylhexanoin — common questions

What is Triethylhexanoin in skincare?

Glyceryl triesters are a group of ingredients derived from glycerin and fatty acids. Specific examples include Trilaurin (from glycerin and lauric acid), Tristearin (from glycerin and stearic acid), and others such as Triethylhexanoin, Triundecanoin, and Glyceryl Stearate Diacetate. These ingredients are commonly found in a wide range of cosmetic products, including makeup, creams and lotions, deodorants, sunscreens, hair conditioners, and skin cleansing formulations.

What does Triethylhexanoin do? / Functions of Triethylhexanoin?

Common functions: FRAGRANCE, HAIR CONDITIONING, PERFUMING, SKIN CONDITIONING.

What is the comedogenic rating of Triethylhexanoin? / Is Triethylhexanoin comedogenic?
1 1/5 — Very low risk

Triethylhexanoin has a comedogenic rating of 1 out of 5. A rating of 1 means it is unlikely to clog pores.

Does it clog pores?
Unlikely to Clog Pores

Triethylhexanoin is unlikely to clog pores (rating 1/5).

Is Triethylhexanoin safe for skin?
1 1/5 — Very low risk

Triethylhexanoin has a safety rating of 1 out of 5. A rating of 1 means it is generally considered safe for most skin types. Note: CIR-reviewed ester emollient; low irritation/sensitization potential and no strong evidence of carcinogenicity or endocrine disruption at cosmetic use levels. It has a low comedogenic rating, indicati

Is Triethylhexanoin good for sensitive skin?
1 1/5 — Very low risk

Triethylhexanoin has an irritancy rating of 1 out of 5. A rating of 1 means it is generally well-tolerated.

What are the side effects of Triethylhexanoin in skincare?

Known considerations: CIR-reviewed ester emollient; low irritation/sensitization potential and no strong evidence of carcinogenicity or endocrine disruption at cosmetic use levels. It has a low comedogenic rating, indicating minimal likelihood of pore blockage, and is generally considered safe for use in cosmetics.

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