SkinWis
SkinWis Scientific

Curology Custom Rx (0.02% Tretinoin, 5% Azelaic Acid, 4% Niacinamide) vs Curology Custom Serum (Niacinamide 4%, Clindamycin 1%, Azelaic 4%)

Comparing Curology Custom Rx (0.02% Tretinoin, 5% Azelaic Acid, 4% Niacinamide) versus Curology Custom Serum (Niacinamide 4%, Clindamycin 1%, Azelaic 4%) — shared ingredients, unique components, comedogenic & irritancy ratings and unique benefits.

Comparison Overview

Custom Rx (0.02% Tretinoin, 5% Azelaic Acid, 4% Niacinamide)

Product 1

Curology Custom Rx (0.02% Tretinoin, 5% Azelaic Acid, 4% Niacinamide)

vs
Custom Serum (Niacinamide 4%, Clindamycin 1%, Azelaic 4%)

Product 2

Curology Custom Serum (Niacinamide 4%, Clindamycin 1%, Azelaic 4%)

11

Shared Ingredients

3

Unique to Curology Custom Rx (0.02% Tretinoin, 5% Azelaic Acid, 4% Niacinamide)

2

Unique to Curology Custom Serum (Niacinamide 4%, Clindamycin 1%, Azelaic 4%)

Neither product contains highly comedogenic ingredients (rating ≥ 3), making both suitable for acne-prone skin. Curology Custom Serum (Niacinamide 4%, Clindamycin 1%, Azelaic 4%) scores lower on irritancy, which may suit sensitive skin better. Both products share 11 ingredients in common. Curology Custom Rx (0.02% Tretinoin, 5% Azelaic Acid, 4% Niacinamide) has 3 unique ingredients while Curology Custom Serum (Niacinamide 4%, Clindamycin 1%, Azelaic 4%) has 2.

Skin Safety Profile

Product Benefits & Effects

✓Positive — Beneficial effects !Caution — Monitor closely

Custom Rx (0.02% Tretinoin, 5% Azelaic Acid, 4% Niacinamide) Benefits

✓Acne Fighting✓Has Anti-aging properties✓Has skin-brightening properties✓Reduces dark spots!May cause irritation for some skin types!May Worsen Oily Skin for some skin types✓Redness Reducing✓Good For Oily Skin

Custom Serum (Niacinamide 4%, Clindamycin 1%, Azelaic 4%) Benefits

✓Acne Fighting✓Has skin-brightening properties✓Reduces dark spots✓Redness Reducing!May Worsen Oily Skin for some skin types✓Good For Oily Skin

Ingredient Analysis Matrix

⇄ Swap Positions
Scale 1 2 3 4 5 low → high
C = Comedogenic S = Safety risk IR = Irritancy
1

Ingredients — Unique to Curology Custom Rx (0.02% Tretinoin, 5% Azelaic Acid, 4% Niacinamide)

TretinoinCSIRPropylene GlycolCSIRBHTCSIR
2

Ingredients — Unique to Curology Custom Serum (Niacinamide 4%, Clindamycin 1%, Azelaic 4%)

Clindamycin Phosphate 1%CSIRMaltodextrinCSIR

Frequently Asked Questions

Is Curology Custom Rx (0.02% Tretinoin, 5% Azelaic Acid, 4% Niacinamide) better than Curology Custom Serum (Niacinamide 4%, Clindamycin 1%, Azelaic 4%) for sensitive skin?

By comparing Custom Rx (0.02% Tretinoin, 5% Azelaic Acid, 4% Niacinamide) and Custom Serum (Niacinamide 4%, Clindamycin 1%, Azelaic 4%) side-by-side, you can identify which product has fewer irritants and a better safety profile for sensitive skin. Check the irritancy ratings in the comparison matrix above.

Which product, Custom Rx (0.02% Tretinoin, 5% Azelaic Acid, 4% Niacinamide) or Custom Serum (Niacinamide 4%, Clindamycin 1%, Azelaic 4%), is safer for acne-prone skin?

The comparison tool highlights comedogenic (pore-clogging) ingredients in both Custom Rx (0.02% Tretinoin, 5% Azelaic Acid, 4% Niacinamide) and Custom Serum (Niacinamide 4%, Clindamycin 1%, Azelaic 4%). Review the comedogenic ratings above to see which formulation is less likely to cause breakouts.

Do Custom Rx (0.02% Tretinoin, 5% Azelaic Acid, 4% Niacinamide) and Custom Serum (Niacinamide 4%, Clindamycin 1%, Azelaic 4%) share any ingredients?

Our ingredient analysis matrix lists all shared ingredients as well as those unique to either Custom Rx (0.02% Tretinoin, 5% Azelaic Acid, 4% Niacinamide) or Custom Serum (Niacinamide 4%, Clindamycin 1%, Azelaic 4%).

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