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Skincare Ingredient

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Ceramide AP

In Skincare: Is Ceramide AP Safe? Comedogenic Rating & Side Effects

Comedogenicity (pore clogging)
1/5 — Very low risk
Safety (overall safety)
1/5 — Very low risk
Irritancy (skin irritation)
1/5 — Very low risk

Safety Information

Ceramide AP is a skin-identical lipid that supports the maintenance of the skin barrier. According to available data, it is generally considered safe for use in cosmetics with low potential for irritation or comedogenicity. Limited safety data is available for long-term or high-concentration use, but no significant concerns have been reported in typical cosmetic formulations.

Quick Insights

At a glance

  • 01

    Ceramide AP contributes to strengthening the skin's protective barrier.

  • 02

    This ceramide improves skin hydration and enhances its suppleness.

  • 03

    Ceramide AP demonstrates optimal efficacy when used in combination with other ceramides.

Key Benefits

What Ceramide AP does for your skin

2 benefits
Hydration
Anti-Aging

Overview

Ingredient Profile

Ceramide AP is a lipid (fat) molecule naturally found in skin, where it plays a crucial role in maintaining the skin barrier. As part of the broader ceramide family, Ceramide AP helps protect against external stressors and supports skin health. Studies suggest that a decline in this ceramide can be associated with conditions like eczema and psoriasis, so topical application can help strengthen the skin barrier, improve hydration, and promote a more supple appearance. Ceramides are generally most effective when combined with other lipids like fatty acids and cholesterol, and have been deemed safe for use in cosmetics at concentrations between 0.00005-0.2%.
Classifications
Emollient

Role of Ceramide AP

Active Cosmetic Mechanisms

HAIR CONDITIONING

Hair Softener

Improves hair manageability, softness, and appearance

SCIENTIFIC ANALYSIS

// Evidence: Hair conditioning ingredients smooth the cuticle, reduce frizz, and add shine through cationic surfactants (behentrimonium chloride), silicones (dimethicone, amodimethicone), natural oils, and proteins. These deposit on negatively charged damaged sites, neutralizing charge, filling surface irregularities, and providing lubrication. Mechanism involves electrostatic attraction, film formation, and surface smoothing.

SKIN CONDITIONING

Skin Enhancer

Maintains skin in good condition and improves its feel

SCIENTIFIC ANALYSIS

// Evidence: Skin conditioning ingredients enhance appearance, texture, and health of skin through various mechanisms. This broad category encompasses emollients, humectants, occlusives, and other agents that improve skin feel, appearance, and function. May work by moisturizing, smoothing, softening, or protecting skin. Effects include improved tactile properties, enhanced barrier function, and better overall skin condition.

Products

containing Ceramide AP

1781 formulations
Mineral Creme SPF 30 - Sensitive
Mineral Creme SPF 30 - Sensitive
Daylong · sunscreen
Renewing SA Cleanser
Renewing SA Cleanser
CeraVe · cleanser
Hyaluron Shot Sun Care SPF 50+ / PA++++ IRF 20
Hyaluron Shot Sun Care SPF 50+ / PA++++ IRF 20
AMPLE:N · sunscreen

References

Scientific sources

[1]

International Journal of Toxicology, 2020, pages 5S-25S

[2]

International Journal of Molecular Sciences, August 2019, pages 1-15

[3]

Biochimica et Biophysica Acta, October 2014, pages 2473-2483

[4]

Journal of the American Academy of Dermatology, July 2014, pages 177-184

[5]

Pharmaceutical Research, November 2012, pages 538-551

[6]

Journal of Lipid Research, July 2008, pages 1,466-1,476

[7]

Journal of Lipid Research, September 2007, pages 1936-1943

[8]

American Journal of Clinical Dermatology, 2003, pages 107-129

[9]

Journal of Investigative Dermatology, November 2001, pages 1,126-1,136

[10]

Skin Pharmacology and Applied Skin Physiology, September-October 2001, pages 261-271

Semantic Analysis

Similar Ingredients

Ingredients with similar chemical profiles and skincare properties.

Frequently Asked Questions

Ceramide AP — common questions

What is Ceramide AP in skincare?

Ceramide AP, formerly known under the INCI name Ceramide 6 II, is the N-acylated sphingolipid consisting of Phytosphingosine having the D-erythro structure linked to an alpha-hydroxy saturated or unsaturated fatty acid.

What does Ceramide AP do? / Functions of Ceramide AP?

Common functions: HAIR CONDITIONING, SKIN CONDITIONING.

What is the comedogenic rating of Ceramide AP? / Is Ceramide AP comedogenic?
1 1/5 — Very low risk

Ceramide AP has a comedogenic rating of 1 out of 5. A rating of 1 means it is unlikely to clog pores.

Does it clog pores?
Unlikely to Clog Pores

Ceramide AP is unlikely to clog pores (rating 1/5).

Is Ceramide AP safe for skin?
1 1/5 — Very low risk

Ceramide AP has a safety rating of 1 out of 5. A rating of 1 means it is generally considered safe for most skin types. Note: Ceramide AP is a skin-identical lipid that supports the maintenance of the skin barrier. According to available data, it is generally considered safe for use in cosmetics with low potential for irrita

Is Ceramide AP good for sensitive skin?
1 1/5 — Very low risk

Ceramide AP has an irritancy rating of 1 out of 5. A rating of 1 means it is generally well-tolerated.

What are the side effects of Ceramide AP in skincare?

Known considerations: Ceramide AP is a skin-identical lipid that supports the maintenance of the skin barrier. According to available data, it is generally considered safe for use in cosmetics with low potential for irritation or comedogenicity. Limited safety data is available for long-term or high-concentration use, but no significant concerns have been reported in typical cosmetic formulations.

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