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Skincare Ingredient

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Palmitic Acid

In Skincare: Is Palmitic Acid Safe? Comedogenic Rating & Side Effects

Comedogenicity (pore clogging)
4/5 — High risk
Safety (overall safety)
2/5 — Low risk
Irritancy (skin irritation)
2/5 — Low risk

Safety Information

Palmitic acid is generally recognized as safe for use in cosmetics by the Cosmetic Ingredient Review (CIR) Expert Panel at concentrations typically used in formulations. However, due to its comedogenic potential, it may contribute to pore clogging and is not recommended for individuals with acne-prone or highly sensitive skin.

Quick Insights

At a glance

  • 01

    Palmitic acid is a fatty acid naturally present in skin.

  • 02

    As the most prevalent fatty acid, palmitic acid is found across animals, plants, and microorganisms.

  • 03

    Palmitic acid functions as a cleansing detergent, emulsifier, and emollient in cosmetic formulations.

  • 04

    The CIR Expert Panel has determined palmitic acid to be safe for use in cosmetics.

Overview

Ingredient Profile

Palmitic acid is a naturally occurring fatty acid found in both skin and various plant and animal sources. It functions as an emollient, helping to soften and smooth the skin, and can also contribute to cleansing formulations. While it may have a drying effect in some cleansers depending on the formulation, palmitic acid is considered safe for cosmetic use at concentrations up to 13% and assists in stabilizing emulsions within moisturizers.
Classifications
Occlusive/Opacifying Agent
Cleansing Agent
Emulsifier

Data & Research

Scientific Facts

Palmitic acid (C16H32O) is a saturated fatty acid. It can be produced naturally by the human body and is also derived from animal and vegetable fats and oils. Fatty acids play a role in various biological processes, including hormone production involved in regulating blood pressure, blood clotting, and immune response.

Common Uses

Formulation in Palmitic Acid

Fatty acids, including palmitic acid, are utilized in cosmetics for their emollient and thickening effects. They contribute to the texture and feel of products, helping to soften and smooth skin.

Role of Palmitic Acid

Active Cosmetic Mechanisms

SKIN CONDITIONING - EMOLLIENT

Skin Softener

Softens and smooths skin by filling gaps between cells

SCIENTIFIC ANALYSIS

// Evidence: Emollient ingredients create smooth, soft skin by filling spaces between corneocytes in stratum corneum. These include esters (isopropyl palmitate), oils (jojoba, argan), fatty alcohols, and silicones. The mechanism involves spreading on skin surface, filling microscopic irregularities, and creating lubricious film. Effects are immediate tactile improvement and visual smoothing. Emolliency measured by spreading coefficient and skin feel assessments.

SURFACTANT - EMULSIFYING

Emulsifying Surfactant

Blends oil and water phases into stable mixtures

SCIENTIFIC ANALYSIS

// Evidence: Emulsifying surfactants enable creation of stable oil-in-water or water-in-oil emulsions by positioning at oil-water interface, reducing interfacial tension. HLB (hydrophilic-lipophilic balance) determines emulsion type: HLB 3-6 for W/O, HLB 8-18 for O/W emulsions. Examples include polysorbate 80, ceteareth-20, glyceryl stearate. Mechanism involves forming interfacial film preventing droplet coalescence. Often used in combinations with co-emulsifiers (fatty alcohols) creating lamellar structures for enhanced stability.

Products

containing Palmitic Acid

4886 formulations
Men+Care Clean Comfort Body and Face Wash
Men+Care Clean Comfort Body and Face Wash
Dove · body-skincare
Olive Real Cleansing Foam
Olive Real Cleansing Foam
innisfree · cleanser
Liftactiv Supreme
Liftactiv Supreme
Vichy · moisturizer

References

Scientific sources

[1]

Journal of Archives in Military Medicine, November 2020

[2]

PLoS One, October 2018, ePublication

[3]

Biophysical Chemistry, August 2010, issues 1-3, pages 144-156

[4]

Journal of Korean Medical Science, June 2010, pages 980-983

[5]

Dermaviduals, 2003, issue 4, pages 54-56

Semantic Analysis

Similar Ingredients

Ingredients with similar chemical profiles and skincare properties.

Frequently Asked Questions

Palmitic Acid — common questions

What is Palmitic Acid in skincare?

Palmitic acid is a saturated fatty acid that occurs naturally in animal and vegetable fats and oils. It’s often found alongside other fatty acids like stearic acid, oleic acid, lauric acid, and myristic acid. These fatty acids are commonly used in cosmetic formulations such as creams, lotions, and pastes to provide emollient and thickening properties.

What does Palmitic Acid do? / Functions of Palmitic Acid?

Common functions: SKIN CONDITIONING - EMOLLIENT, SURFACTANT - EMULSIFYING.

What is the comedogenic rating of Palmitic Acid? / Is Palmitic Acid comedogenic?
4 4/5 — High risk

Palmitic Acid has a comedogenic rating of 4 out of 5. This ingredient appears to be comedogenic. A rating of 4 means it has high pore-clogging potential.

Does it clog pores?
Likely to Clog Pores

This ingredient appears to be comedogenic (rating 4/5).

Is Palmitic Acid safe for skin?
2 2/5 — Low risk

Palmitic Acid has a safety rating of 2 out of 5. A rating of 2 means it is generally considered safe for most skin types. Note: Palmitic acid is generally recognized as safe for use in cosmetics by the Cosmetic Ingredient Review (CIR) Expert Panel at concentrations typically used in formulations. However, due to its comedogeni

Is Palmitic Acid good for sensitive skin?
2 2/5 — Low risk

Palmitic Acid has an irritancy rating of 2 out of 5. A rating of 2 means it is generally well-tolerated.

What are the side effects of Palmitic Acid in skincare?

Known considerations: Palmitic acid is generally recognized as safe for use in cosmetics by the Cosmetic Ingredient Review (CIR) Expert Panel at concentrations typically used in formulations. However, due to its comedogenic potential, it may contribute to pore clogging and is not recommended for individuals with acne-prone or highly sensitive skin. Additional risks: potential pore-clogging (comedogenic rating 4/5).

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