What are the key ingredients in C 15 Serum Advance Plus?

C 15 Serum Advance Plus contains 8 ingredients. Key actives include: Water, Sodium Hyaluronate, Ascorbic Acid, Propylene Glycol, Zinc Sulfate, and more.

Does C 15 Serum Advance Plus contain comedogenic or pore-clogging ingredients?

Based on ingredient analysis, C 15 Serum Advance Plus does not contain known comedogenic or irritating ingredients and is generally considered safe for acne-prone skin.

How is the safety of C 15 Serum Advance Plus rated?

Safety ratings for C 15 Serum Advance Plus are calculated based on individual ingredient analysis, covering comedogenicity, irritancy, and overall safety scores. See the full breakdown at https://www.skinwis.com/product/is-clinical-c-15-serum-advance-plus.

Where can I find the full ingredient list for C 15 Serum Advance Plus?

The complete ingredient list, safety analysis, and community reviews for C 15 Serum Advance Plus are available on SkinWis at https://www.skinwis.com/product/is-clinical-c-15-serum-advance-plus.

Brand iS Clinical

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C 15 Serum Advance Plus

Updated on: 13/07/2025

Total Ingredients

analysed

7 of 8

Skin-Safe

low risk

0 of 8

Potential Irritants

may irritate sensitive skin

0 of 8

Potential Pore-Clogging

comedogenic risk

About this product

8 ingredients

none potential irritant

none pore-clogging

Contains Vitamin C and Vitamin C. Mostly fragrance‑free. Formula aimed at oily and acne-prone skin. Patch-test if you have very reactive skin.

Formulation Analysis

Click any ingredient to view full details

C: Comedogenic·S: Safety·Ir: Irritancy

1 Very safe

2 Safe

3 Moderate

4 Risky

5 Avoid

C: Comedogenic·S: Safety·Ir: Irritancy

1 Very safe

2 Safe

3 Moderate

4 Risky

5 Avoid

Water

Comedogenic: Very low risk

Safety: Very low risk

Irritancy: Very low risk

Plaque Prevention Agent Skin Enhancer Ingredient Dissolver

Sodium Hyaluronate

Comedogenic: Very low risk

Safety: Very low risk

Irritancy: Very low risk

Skin Enhancer Moisture Magnet

Ascorbic Acid

Comedogenic: Very low risk

Safety: Low risk

Irritancy: Moderate risk

Anti-Aging Protector Skin Enhancer pH Stabilizer +1

Propylene Glycol

Comedogenic: Very low risk

Safety: Low risk

Irritancy: Moderate risk

General Skin Improver Moisture Magnet Thickness Regulator +3

Zinc Sulfate

Safety: Low risk

Irritancy: Moderate risk

Plaque Prevention Agent Germ Fighter Pore Tightener +1

Bioflavonoids

Safety: Low risk

Skin Enhancer Calming Agent

Phenoxyethanol

Safety: Low risk

Irritancy: Moderate risk

Product Protector Germ Fighter

Vitamin C

Ingredient Name	Safety Profile	Functionality
01 Water	C 1 Comedogenic: Very low risk S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Plaque Prevention Agent Skin Enhancer +1
02 Sodium Hyaluronate	C 1 Comedogenic: Very low risk S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Skin Enhancer Moisture Magnet
03 Ascorbic Acid	C 1 Comedogenic: Very low risk S 2 Safety: Low risk Ir 3 Irritancy: Moderate risk	Anti-Aging Protector Skin Enhancer +2
04 Propylene Glycol	C 1 Comedogenic: Very low risk S 2 Safety: Low risk Ir 3 Irritancy: Moderate risk	General Skin Improver Moisture Magnet +4
05 Zinc Sulfate	S 2 Safety: Low risk Ir 3 Irritancy: Moderate risk	Plaque Prevention Agent Germ Fighter +2
06 Bioflavonoids	S 2 Safety: Low risk	Skin Enhancer Calming Agent
07 Phenoxyethanol	S 2 Safety: Low risk Ir 3 Irritancy: Moderate risk	Product Protector Germ Fighter
08 Vitamin C		N/A

Community

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Common Questions

Frequently Asked Questions

Is iS Clinical C 15 Serum Advance Plus comedogenic?

Appears Non-Comedogenic C 15 Serum Advance Plus appears to be non-comedogenic based on our ingredient analysis. None of its 8 ingredients carry a high comedogenic rating, making it generally suitable for acne-prone and oily skin types.

Is iS Clinical a good skincare brand?

US professional skincare brand focusing on anti-aging and clinical results. Assess products individually by reviewing their ingredient lists and community feedback. Read more about iS Clinical.

Is iS Clinical C 15 Serum Advance Plus safe for sensitive skin?

Appears Suitable for Sensitive Skin C 15 Serum Advance Plus appears suitable for sensitive skin based on its ingredient profile. No common irritants detected among its 8 ingredients. Always patch test when trying a new product.

Does iS Clinical C 15 Serum Advance Plus clog pores?

Unlikely to Clog Pores Based on our analysis, C 15 Serum Advance Plus is unlikely to clog pores. None of its 8 ingredients have a comedogenic rating above 2.

Who makes iS Clinical C 15 Serum Advance Plus?

This product is from iS Clinical. See more products from iS Clinical.

What are the ingredients in iS Clinical C 15 Serum Advance Plus?

C 15 Serum Advance Plus contains 8 ingredients. The first ingredients listed are <a href="/ingredient/water" class="font-bold underline hover:text-cyan-700">Water</a>, <a href="/ingredient/sodium-hyaluronate" class="font-bold underline hover:text-cyan-700">Sodium Hyaluronate</a>, <a href="/ingredient/ascorbic-acid" class="font-bold underline hover:text-cyan-700">Ascorbic Acid</a>, <a href="/ingredient/propylene-glycol" class="font-bold underline hover:text-cyan-700">Propylene Glycol</a> and <a href="/ingredient/zinc-sulfate" class="font-bold underline hover:text-cyan-700">Zinc Sulfate</a>. Each ingredient includes a comedogenic rating, irritancy rating, and safety score. View the full annotated ingredient list above.

What do users say about iS Clinical C 15 Serum Advance Plus?

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