What are the key ingredients in Collagen Hand Cream?

Collagen Hand Cream contains 40 ingredients. Key actives include: Water, Cetyl Alcohol, Glycerin, Dimethicone, Butyrospermum Parkii Butter, and more.

Does Collagen Hand Cream contain comedogenic or pore-clogging ingredients?

Collagen Hand Cream contains potentially comedogenic or irritating ingredients: Parfum. Always patch test before full use.

How is the safety of Collagen Hand Cream rated?

Safety ratings for Collagen Hand Cream are calculated based on individual ingredient analysis, covering comedogenicity, irritancy, and overall safety scores. See the full breakdown at https://www.skinwis.com/product/advanced-clinicals-collagen-hand-cream.

Where can I find the full ingredient list for Collagen Hand Cream?

The complete ingredient list, safety analysis, and community reviews for Collagen Hand Cream are available on SkinWis at https://www.skinwis.com/product/advanced-clinicals-collagen-hand-cream.

Brand ADVANCED CLINICALS

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Collagen Hand Cream

Updated on: 12/12/2025

Total Ingredients

analysed

33 of 40

Skin-Safe

low risk

2 of 40

Potential Irritants

may irritate sensitive skin

1 of 40

Potential Pore-Clogging

comedogenic risk

About this product

40 ingredients

2 potential irritant

1 pore-clogging

Contains Peptides. Contains fragrance — patch test if sensitive. Formula aimed at skin types that tolerate moderate comedogenic ingredients. Patch-test if you have very reactive skin.

Formulation Analysis

Click any ingredient to view full details

C: Comedogenic·S: Safety·Ir: Irritancy

1 Very safe

2 Safe

3 Moderate

4 Risky

5 Avoid

C: Comedogenic·S: Safety·Ir: Irritancy

1 Very safe

2 Safe

3 Moderate

4 Risky

5 Avoid

Water

Comedogenic: Very low risk

Safety: Very low risk

Irritancy: Very low risk

Plaque Prevention Agent Skin Enhancer Ingredient Dissolver

Cetyl Alcohol

Comedogenic: Low risk

Safety: Very low risk

Irritancy: Very low risk

Cloudiness Creator Foam Enhancer Cleansing Surfactant +5

Glycerin

Comedogenic: Very low risk

Safety: Very low risk

Irritancy: Very low risk

Fragrance Provider Moisture Magnet Thickness Regulator +7

Dimethicone

Comedogenic: Very low risk

Safety: Very low risk

Irritancy: Very low risk

Skin Enhancer Skin Softener Defensive Shield +1

Butyrospermum Parkii Butter

Comedogenic: Very low risk

Safety: Very low risk

Irritancy: Very low risk

Skin Enhancer Thickness Regulator

Ceteareth-20

Safety: Low risk

Irritancy: Low risk

Cleansing Surfactant Dirt & Oil Remover Emulsifying Surfactant

Aloe Barbadensis Leaf Juice

Comedogenic: Very low risk

Safety: Low risk

Irritancy: Low risk

Skin Enhancer

Oryza Sativa Extract

Safety: Very low risk

Irritancy: Very low risk

Volume Builder Skin Enhancer Polishing & Scrubbing Agent +2

Glycine Max Seed Extract

Safety: Very low risk

Irritancy: Very low risk

Skin Enhancer Hair Softener Defensive Shield

Daucus Carota Sativa Root Extract

Safety: Low risk

Irritancy: Low risk

Skin Enhancer

Chenopodium Quinoa Seed Extract

Safety: Very low risk

Irritancy: Very low risk

Skin Enhancer

Panax Ginseng Root Extract

Safety: Low risk

Irritancy: Low risk

Revitalizer Hair Softener Skin Softener +1

Caulerpa Lentillifera Extract

Protective Coating Agent

Acetyl Hexapeptide-8

Safety: Low risk

Skin Enhancer Moisture Magnet

Camellia Sinensis Leaf Extract

Comedogenic: Very low risk

Safety: Very low risk

Irritancy: Very low risk

Anti-Aging Protector UV Ray Absorber Skin Enhancer +8

Pyrus Malus Fruit Extract

Safety: Low risk

Irritancy: Low risk

Skin Enhancer

Helianthus Annuus Extract

Safety: Very low risk

Irritancy: Very low risk

Skin Enhancer Hair Softener Skin Softener

Oryza Sativa Bran Extract

Safety: Very low risk

Irritancy: Very low risk

Skin Enhancer Defensive Shield

Rosmarinus Officinalis Leaf Extract

Safety: Low risk

Irritancy: Moderate risk

Skin Enhancer Germ Fighter Scent Provider

Tocopherol

Comedogenic: Low risk

Safety: Low risk

Irritancy: Low risk

General Skin Improver Moisture Barrier Creator Anti-Aging Protector +1

Cetearyl Ethylhexanoate

Comedogenic: Low risk

Safety: Low risk

Irritancy: Very low risk

Skin Enhancer Hair Softener Skin Softener

Isopropyl Myristate

Comedogenic: Very high risk

Safety: Low risk

Irritancy: Low risk

Fragrance Provider Ingredient Binder Scent Provider +1

Cetearyl Phosphate

Comedogenic: Low risk

Safety: Low risk

Irritancy: Low risk

Skin Enhancer

Polyglyceryl-2 Stearate

Comedogenic: Low risk

Safety: Very low risk

Irritancy: Very low risk

Emulsifying Surfactant

Synthetic Beeswax

Safety: Very low risk

Irritancy: Very low risk

Thickness Regulator Ingredient Binder Emulsion Stabilizer

Carbomer

Comedogenic: Very low risk

Safety: Very low risk

Irritancy: Very low risk

Gel Structure Builder Thickness Regulator Emulsion Stabilizer

Xanthan Gum

Comedogenic: Very low risk

Safety: Very low risk

Irritancy: Very low risk

Cleansing Surfactant Skin Enhancer Gel Structure Builder +4

Disodium EDTA

Safety: Low risk

Irritancy: Very low risk

Thickness Regulator Metal Ion Binder

Butylene Glycol

Comedogenic: Very low risk

Safety: Very low risk

Irritancy: Low risk

Skin Enhancer Moisture Magnet Thickness Regulator +2

Parfum

Safety: Moderate risk

Irritancy: High risk

Fragrance Provider Scent Provider

Phenoxyethanol

Safety: Low risk

Irritancy: Moderate risk

Product Protector Germ Fighter

Ethylhexylglycerin

Comedogenic: Very low risk

Safety: Low risk

Irritancy: Low risk

Skin Enhancer Odor Neutralizer

Caprylyl Glycol

Comedogenic: Very low risk

Safety: Low risk

Irritancy: Low risk

Skin Enhancer Hair Softener Odor Neutralizer +1

Hexylene Glycol

Safety: Low risk

Irritancy: Low risk

Cleansing Surfactant Fragrance Provider Skin Enhancer +2

Sodium Hydroxide

Safety: Low risk

Irritancy: High risk

pH Stabilizer Alcohol Treatment Agent

Ingredient Name	Safety Profile	Functionality
01 Water	C 1 Comedogenic: Very low risk S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Plaque Prevention Agent Skin Enhancer +1
02 Cetyl Alcohol	C 2 Comedogenic: Low risk S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Cloudiness Creator Foam Enhancer +6
03 Glycerin	C 1 Comedogenic: Very low risk S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Fragrance Provider Moisture Magnet +8
04 Dimethicone	C 1 Comedogenic: Very low risk S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Skin Enhancer Skin Softener +2
05 Butyrospermum Parkii Butter	C 1 Comedogenic: Very low risk S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Skin Enhancer Thickness Regulator
06 Ceteareth-20	S 2 Safety: Low risk Ir 2 Irritancy: Low risk	Cleansing Surfactant Dirt & Oil Remover +1
07 Aloe Barbadensis Leaf Juice	C 1 Comedogenic: Very low risk S 2 Safety: Low risk Ir 2 Irritancy: Low risk	Skin Enhancer
08 Oryza Sativa Extract	S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Volume Builder Skin Enhancer +3
09 Glycine Max Seed Extract	S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Skin Enhancer Hair Softener +1
10 Daucus Carota Sativa Root Extract	S 2 Safety: Low risk Ir 2 Irritancy: Low risk	Skin Enhancer
11 Chenopodium Quinoa Seed Extract	S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Skin Enhancer
12 Panax Ginseng Root Extract	S 2 Safety: Low risk Ir 2 Irritancy: Low risk	Revitalizer Hair Softener +2
13 Caulerpa Lentillifera Extract		Protective Coating Agent
14 Acetyl Hexapeptide-8	S 2 Safety: Low risk	Skin Enhancer Moisture Magnet
15 Camellia Sinensis Leaf Extract	C 1 Comedogenic: Very low risk S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Anti-Aging Protector UV Ray Absorber +9
16 Pyrus Malus Fruit Extract	S 2 Safety: Low risk Ir 2 Irritancy: Low risk	Skin Enhancer
17 Helianthus Annuus Extract	S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Skin Enhancer Hair Softener +1
18 Oryza Sativa Bran Extract	S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Skin Enhancer Defensive Shield
19 Rosmarinus Officinalis Leaf Extract	S 2 Safety: Low risk Ir 3 Irritancy: Moderate risk	Skin Enhancer Germ Fighter +1
20 Tocopherol	C 2 Comedogenic: Low risk S 2 Safety: Low risk Ir 2 Irritancy: Low risk	General Skin Improver Moisture Barrier Creator +2
21 Cetearyl Ethylhexanoate	C 2 Comedogenic: Low risk S 2 Safety: Low risk Ir 1 Irritancy: Very low risk	Skin Enhancer Hair Softener +1
22 Isopropyl Myristate	C 5 Comedogenic: Very high risk S 2 Safety: Low risk Ir 2 Irritancy: Low risk	Fragrance Provider Ingredient Binder +2
23 Cetearyl Phosphate	C 2 Comedogenic: Low risk S 2 Safety: Low risk Ir 2 Irritancy: Low risk	Skin Enhancer
24 Polyglyceryl-2 Stearate	C 2 Comedogenic: Low risk S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Emulsifying Surfactant
25 Synthetic Beeswax	S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Thickness Regulator Ingredient Binder +1
26 Carbomer	C 1 Comedogenic: Very low risk S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Gel Structure Builder Thickness Regulator +1
27 Xanthan Gum	C 1 Comedogenic: Very low risk S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Cleansing Surfactant Skin Enhancer +5
28 Disodium EDTA	S 2 Safety: Low risk Ir 1 Irritancy: Very low risk	Thickness Regulator Metal Ion Binder
29 Butylene Glycol	C 1 Comedogenic: Very low risk S 1 Safety: Very low risk Ir 2 Irritancy: Low risk	Skin Enhancer Moisture Magnet +3
30 Parfum	S 3 Safety: Moderate risk Ir 4 Irritancy: High risk	Fragrance Provider Scent Provider
31 Phenoxyethanol	S 2 Safety: Low risk Ir 3 Irritancy: Moderate risk	Product Protector Germ Fighter
32 Ethylhexylglycerin	C 1 Comedogenic: Very low risk S 2 Safety: Low risk Ir 2 Irritancy: Low risk	Skin Enhancer Odor Neutralizer
33 Caprylyl Glycol	C 1 Comedogenic: Very low risk S 2 Safety: Low risk Ir 2 Irritancy: Low risk	Skin Enhancer Hair Softener +2
34 Hexylene Glycol	S 2 Safety: Low risk Ir 2 Irritancy: Low risk	Cleansing Surfactant Fragrance Provider +3
35 Sodium Hydroxide	S 2 Safety: Low risk Ir 4 Irritancy: High risk	pH Stabilizer Alcohol Treatment Agent
36 Aloe Vera leaf juice		N/A
37 Carrot root extract		N/A
38 Rice bran extract		N/A
39 Rosemary Extract		N/A
40 Vitamin E		N/A

Potential Irritants

1 flagged

Parfum

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Common Questions

Frequently Asked Questions

Is ADVANCED CLINICALS Collagen Hand Cream comedogenic?

Appears To Be Comedogenic Collagen Hand Cream appears to be comedogenic. It contains 1 ingredient with a high comedogenic rating (4–5) that are likely to clog pores , including <a href="/ingredient/isopropyl-myristate" class="font-bold underline hover:text-cyan-700">Isopropyl Myristate</a> . It may not be suitable for acne-prone skin.

Is ADVANCED CLINICALS a good skincare brand?

US skincare brand offering spa-sized anti-aging and treatment products. ADVANCED CLINICALS makes products such as Collagen Hand Cream that include some ingredients which may be problematic for sensitive or acne-prone skin. Check individual product ingredient lists and community reviews before deciding. Read more about ADVANCED CLINICALS.

Is ADVANCED CLINICALS Collagen Hand Cream safe for sensitive skin?

Use with Caution Collagen Hand Cream may not be ideal for sensitive skin. It contains 2 potential irritant s including <a href="/ingredient/parfum" class="font-bold underline hover:text-cyan-700">Parfum</a> and <a href="/ingredient/sodium-hydroxide" class="font-bold underline hover:text-cyan-700">Sodium Hydroxide</a> . Common triggers like Fragrance, Limonene, and Linalool can cause redness or reactions in sensitive or barrier-compromised skin. We recommend patch testing before full use.

Does ADVANCED CLINICALS Collagen Hand Cream clog pores?

Potential Pore-Cloggers Present Collagen Hand Cream contains 1 ingredient with a comedogenic rating of 3 or higher that may clog pores , including <a href="/ingredient/isopropyl-myristate" class="font-bold underline hover:text-cyan-700">Isopropyl Myristate</a> . Every ingredient's comedogenic rating is listed above.

Who makes ADVANCED CLINICALS Collagen Hand Cream?

This product is from ADVANCED CLINICALS. See more products from ADVANCED CLINICALS.

What are the ingredients in ADVANCED CLINICALS Collagen Hand Cream?

Collagen Hand Cream contains 40 ingredients. The first ingredients listed are <a href="/ingredient/water" class="font-bold underline hover:text-cyan-700">Water</a>, <a href="/ingredient/cetyl-alcohol" class="font-bold underline hover:text-cyan-700">Cetyl Alcohol</a>, <a href="/ingredient/glycerin" class="font-bold underline hover:text-cyan-700">Glycerin</a>, <a href="/ingredient/dimethicone" class="font-bold underline hover:text-cyan-700">Dimethicone</a> and <a href="/ingredient/butyrospermum-parkii-butter" class="font-bold underline hover:text-cyan-700">Butyrospermum Parkii Butter</a>. Each ingredient includes a comedogenic rating, irritancy rating, and safety score. View the full annotated ingredient list above.

What do users say about ADVANCED CLINICALS Collagen Hand Cream?

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