What are the key ingredients in Targeted Treatment Sheer Physical Protection Cream SPF 50?

Targeted Treatment Sheer Physical Protection Cream SPF 50 contains 38 ingredients. Key actives include: Titanium Dioxide, Zinc Oxide, Water, Dimethicone, Isododecane, and more.

Does Targeted Treatment Sheer Physical Protection Cream SPF 50 contain comedogenic or pore-clogging ingredients?

Based on ingredient analysis, Targeted Treatment Sheer Physical Protection Cream SPF 50 does not contain known comedogenic or irritating ingredients and is generally considered safe for acne-prone skin.

How is the safety of Targeted Treatment Sheer Physical Protection Cream SPF 50 rated?

Safety ratings for Targeted Treatment Sheer Physical Protection Cream SPF 50 are calculated based on individual ingredient analysis, covering comedogenicity, irritancy, and overall safety scores. See the full breakdown at https://www.skinwis.com/product/neostrata-targeted-treatment-sheer-physical-protection-cream-spf-50.

Where can I find the full ingredient list for Targeted Treatment Sheer Physical Protection Cream SPF 50?

The complete ingredient list, safety analysis, and community reviews for Targeted Treatment Sheer Physical Protection Cream SPF 50 are available on SkinWis at https://www.skinwis.com/product/neostrata-targeted-treatment-sheer-physical-protection-cream-spf-50.

Brand NEOSTRATA

Compare

Targeted Treatment Sheer Physical Protection Cream SPF 50

Updated on: 25/06/2025

Total Ingredients

analysed

31 of 38

Skin-Safe

low risk

2 of 38

Potential Irritants

may irritate sensitive skin

0 of 38

Potential Pore-Clogging

comedogenic risk

About this product

38 ingredients

2 potential irritant

none pore-clogging

Contains Zinc. Mostly fragrance‑free. Formula aimed at oily and acne-prone skin. Patch-test if you have very reactive skin.

Formulation Analysis

Click any ingredient to view full details

C: Comedogenic·S: Safety·Ir: Irritancy

1 Very safe

2 Safe

3 Moderate

4 Risky

5 Avoid

C: Comedogenic·S: Safety·Ir: Irritancy

1 Very safe

2 Safe

3 Moderate

4 Risky

5 Avoid

Titanium Dioxide

Comedogenic: Very low risk

Safety: Low risk

Irritancy: Very low risk

Sunscreen Agent Cloudiness Creator UV Ray Absorber +1

Zinc Oxide

Comedogenic: Very low risk

Safety: Very low risk

Irritancy: Very low risk

Volume Builder Sunscreen Agent UV Protector for Products +5

Water

Comedogenic: Very low risk

Safety: Very low risk

Irritancy: Very low risk

Plaque Prevention Agent Skin Enhancer Ingredient Dissolver

Dimethicone

Comedogenic: Very low risk

Safety: Very low risk

Irritancy: Very low risk

Skin Enhancer Skin Softener Defensive Shield +1

Isododecane

Comedogenic: Very low risk

Safety: Low risk

Irritancy: Very low risk

Fragrance Provider Ingredient Dissolver Skin Softener

C12-15 Alkyl Benzoate

Comedogenic: Low risk

Safety: Very low risk

Irritancy: Very low risk

Skin Enhancer Germ Fighter Skin Softener

Hydrogenated Polydecene

Comedogenic: Very low risk

Safety: Very low risk

Irritancy: Very low risk

Fragrance Provider Skin Enhancer Ingredient Dissolver +3

Butyloctyl Salicylate

Safety: Low risk

Irritancy: Low risk

Skin Enhancer Ingredient Dissolver Hair Softener

Gluconolactone

Comedogenic: Very low risk

Safety: Very low risk

Irritancy: Low risk

Skin Enhancer Metal Ion Binder

Styrene/Acrylates Copolymer

Safety: Low risk

Cloudiness Creator Protective Coating Agent

Alumina

Safety: Very low risk

Irritancy: Low risk

Volume Builder Cloudiness Creator Thickness Regulator +3

Ammonium Hydroxide

Safety: Moderate risk

Irritancy: High risk

pH Stabilizer Alcohol Treatment Agent

Lactobionic Acid

Safety: Low risk

Irritancy: Low risk

pH Stabilizer

Peg-9 Polydimethylsiloxyethyl Dimethicone

Safety: Low risk

Irritancy: Low risk

Skin Enhancer Emulsifying Surfactant

Phenethyl Benzoate

Fragrance Provider Skin Softener

Nylon-12

Comedogenic: Very low risk

Safety: Low risk

Irritancy: Very low risk

Volume Builder Cloudiness Creator Thickness Regulator

Tocopheryl Acetate

Comedogenic: Low risk

Safety: Very low risk

Irritancy: Low risk

Anti-Aging Protector Skin Enhancer

Epigallocatechin Gallate

Safety: Low risk

Irritancy: Low risk

Anti-Aging Protector

Egg

Safety: Moderate risk

Irritancy: Moderate risk

Skin Enhancer Hair Softener

Polyhydroxystearic Acid

Safety: Low risk

Emulsifying Surfactant

Ethylhexylglycerin

Comedogenic: Very low risk

Safety: Low risk

Irritancy: Low risk

Skin Enhancer Odor Neutralizer

Tocopherol

Comedogenic: Low risk

Safety: Low risk

Irritancy: Low risk

General Skin Improver Moisture Barrier Creator Anti-Aging Protector +1

Dimethicone/Peg-10/15 Crosspolymer

Comedogenic: Very low risk

Safety: Very low risk

Irritancy: Very low risk

Cloudiness Creator Protective Coating Agent

Methicone

Comedogenic: Very low risk

Safety: Very low risk

Irritancy: Very low risk

Skin Enhancer Static Eliminator Skin Softener

Isohexadecane

Comedogenic: Very low risk

Safety: Very low risk

Irritancy: Very low risk

Ingredient Dissolver Skin Softener

Sodium Citrate

Comedogenic: Very low risk

Safety: Very low risk

Irritancy: Very low risk

pH Stabilizer Metal Ion Binder Scent Provider

Disteardimonium Hectorite

Safety: Very low risk

Irritancy: Very low risk

UV Protector for Products Thickness Regulator

Magnesium Sulfate

Safety: Low risk

Irritancy: Low risk

Volume Builder

Dipropylene Glycol

Comedogenic: Very low risk

Safety: Very low risk

Irritancy: Low risk

Fragrance Provider Thickness Regulator Ingredient Dissolver +1

Propylene Carbonate

Safety: Low risk

Irritancy: Low risk

Thickness Regulator Ingredient Dissolver

Sodium Bisulfite

Safety: Moderate risk

Irritancy: High risk

Product Protector Anti-Aging Protector Texture Modifier +1

Triethoxycaprylylsilane

Safety: Low risk

Ingredient Binder

Phenoxyethanol

Safety: Low risk

Irritancy: Moderate risk

Product Protector Germ Fighter

Ci 77492

Safety: Very low risk

Safety: Very low risk

Color Provider

Form of vitamin E

Vitamin E

Ingredient Name	Safety Profile	Functionality
01 Titanium Dioxide	C 1 Comedogenic: Very low risk S 2 Safety: Low risk Ir 1 Irritancy: Very low risk	Sunscreen Agent Cloudiness Creator +2
02 Zinc Oxide	C 1 Comedogenic: Very low risk S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Volume Builder Sunscreen Agent +6
03 Water	C 1 Comedogenic: Very low risk S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Plaque Prevention Agent Skin Enhancer +1
04 Dimethicone	C 1 Comedogenic: Very low risk S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Skin Enhancer Skin Softener +2
05 Isododecane	C 1 Comedogenic: Very low risk S 2 Safety: Low risk Ir 1 Irritancy: Very low risk	Fragrance Provider Ingredient Dissolver +1
06 C12-15 Alkyl Benzoate	C 2 Comedogenic: Low risk S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Skin Enhancer Germ Fighter +1
07 Hydrogenated Polydecene	C 1 Comedogenic: Very low risk S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Fragrance Provider Skin Enhancer +4
08 Butyloctyl Salicylate	S 2 Safety: Low risk Ir 2 Irritancy: Low risk	Skin Enhancer Ingredient Dissolver +1
09 Gluconolactone	C 1 Comedogenic: Very low risk S 1 Safety: Very low risk Ir 2 Irritancy: Low risk	Skin Enhancer Metal Ion Binder
10 Styrene/Acrylates Copolymer	S 2 Safety: Low risk	Cloudiness Creator Protective Coating Agent
11 Alumina	S 1 Safety: Very low risk Ir 2 Irritancy: Low risk	Volume Builder Cloudiness Creator +4
12 Ammonium Hydroxide	S 3 Safety: Moderate risk Ir 4 Irritancy: High risk	pH Stabilizer Alcohol Treatment Agent
13 Lactobionic Acid	S 2 Safety: Low risk Ir 2 Irritancy: Low risk	pH Stabilizer
14 Peg-9 Polydimethylsiloxyethyl Dimethicone	S 2 Safety: Low risk Ir 2 Irritancy: Low risk	Skin Enhancer Emulsifying Surfactant
15 Phenethyl Benzoate		Fragrance Provider Skin Softener
16 Nylon-12	C 1 Comedogenic: Very low risk S 2 Safety: Low risk Ir 1 Irritancy: Very low risk	Volume Builder Cloudiness Creator +1
17 Tocopheryl Acetate	C 2 Comedogenic: Low risk S 1 Safety: Very low risk Ir 2 Irritancy: Low risk	Anti-Aging Protector Skin Enhancer
18 Epigallocatechin Gallate	S 2 Safety: Low risk Ir 2 Irritancy: Low risk	Anti-Aging Protector
19 Egg	S 3 Safety: Moderate risk Ir 3 Irritancy: Moderate risk	Skin Enhancer Hair Softener
20 Polyhydroxystearic Acid	S 2 Safety: Low risk	Emulsifying Surfactant
21 Ethylhexylglycerin	C 1 Comedogenic: Very low risk S 2 Safety: Low risk Ir 2 Irritancy: Low risk	Skin Enhancer Odor Neutralizer
22 Tocopherol	C 2 Comedogenic: Low risk S 2 Safety: Low risk Ir 2 Irritancy: Low risk	General Skin Improver Moisture Barrier Creator +2
23 Dimethicone/Peg-10/15 Crosspolymer	C 1 Comedogenic: Very low risk S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Cloudiness Creator Protective Coating Agent
24 Methicone	C 1 Comedogenic: Very low risk S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Skin Enhancer Static Eliminator +1
25 Isohexadecane	C 1 Comedogenic: Very low risk S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Ingredient Dissolver Skin Softener
26 Sodium Citrate	C 1 Comedogenic: Very low risk S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	pH Stabilizer Metal Ion Binder +1
27 Disteardimonium Hectorite	S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	UV Protector for Products Thickness Regulator
28 Magnesium Sulfate	S 2 Safety: Low risk Ir 2 Irritancy: Low risk	Volume Builder
29 Dipropylene Glycol	C 1 Comedogenic: Very low risk S 1 Safety: Very low risk Ir 2 Irritancy: Low risk	Fragrance Provider Thickness Regulator +2
30 Propylene Carbonate	S 2 Safety: Low risk Ir 2 Irritancy: Low risk	Thickness Regulator Ingredient Dissolver
31 Sodium Bisulfite	S 3 Safety: Moderate risk Ir 4 Irritancy: High risk	Product Protector Anti-Aging Protector +2
32 Triethoxycaprylylsilane	S 2 Safety: Low risk	Ingredient Binder
33 Phenoxyethanol	S 2 Safety: Low risk Ir 3 Irritancy: Moderate risk	Product Protector Germ Fighter
34 Ci 77492	S 1 Safety: Very low risk	Color Provider
35 Ci 77491		Color Provider
36 Ci 77499	S 1 Safety: Very low risk	Color Provider
37 Form of vitamin E		N/A
38 Vitamin E		N/A

Community

NEOSTRATA Targeted Treatment Sheer Physical Protection Cream SPF 50 Reviews

Be the first to review

No reviews yet

Be the first to share your experience!

Common Questions

Frequently Asked Questions

Is NEOSTRATA Targeted Treatment Sheer Physical Protection Cream SPF 50 comedogenic?

Appears Non-Comedogenic Targeted Treatment Sheer Physical Protection Cream SPF 50 appears to be non-comedogenic based on our ingredient analysis. None of its 38 ingredients carry a high comedogenic rating, making it generally suitable for acne-prone and oily skin types.

Is NEOSTRATA a good skincare brand?

US skincare brand; medical-grade and chemical exfoliants focus. NEOSTRATA makes products such as Targeted Treatment Sheer Physical Protection Cream SPF 50 that include some ingredients which may be problematic for sensitive or acne-prone skin. Check individual product ingredient lists and community reviews before deciding. Read more about NEOSTRATA.

Is NEOSTRATA Targeted Treatment Sheer Physical Protection Cream SPF 50 safe for sensitive skin?

Use with Caution Targeted Treatment Sheer Physical Protection Cream SPF 50 may not be ideal for sensitive skin. It contains 2 potential irritant s including <a href="/ingredient/ammonium-hydroxide" class="font-bold underline hover:text-cyan-700">Ammonium Hydroxide</a> and <a href="/ingredient/sodium-bisulfite" class="font-bold underline hover:text-cyan-700">Sodium Bisulfite</a> . Common triggers like Fragrance, Limonene, and Linalool can cause redness or reactions in sensitive or barrier-compromised skin. We recommend patch testing before full use.

Does NEOSTRATA Targeted Treatment Sheer Physical Protection Cream SPF 50 clog pores?

Unlikely to Clog Pores Based on our analysis, Targeted Treatment Sheer Physical Protection Cream SPF 50 is unlikely to clog pores. None of its 38 ingredients have a comedogenic rating above 2.

Who makes NEOSTRATA Targeted Treatment Sheer Physical Protection Cream SPF 50?

This product is from NEOSTRATA. See more products from NEOSTRATA.

What are the ingredients in NEOSTRATA Targeted Treatment Sheer Physical Protection Cream SPF 50?

Targeted Treatment Sheer Physical Protection Cream SPF 50 contains 38 ingredients. The first ingredients listed are <a href="/ingredient/titanium-dioxide" class="font-bold underline hover:text-cyan-700">Titanium Dioxide</a>, <a href="/ingredient/zinc-oxide" class="font-bold underline hover:text-cyan-700">Zinc Oxide</a>, <a href="/ingredient/water" class="font-bold underline hover:text-cyan-700">Water</a>, <a href="/ingredient/dimethicone" class="font-bold underline hover:text-cyan-700">Dimethicone</a> and <a href="/ingredient/isododecane" class="font-bold underline hover:text-cyan-700">Isododecane</a>. Each ingredient includes a comedogenic rating, irritancy rating, and safety score. View the full annotated ingredient list above.

What do users say about NEOSTRATA Targeted Treatment Sheer Physical Protection Cream SPF 50?

No Reviews Yet Targeted Treatment Sheer Physical Protection Cream SPF 50 does not yet have community reviews on SkinWis. Be the first to share your experience.

Cross-Reference Data