SkinWis
SkinWis Scientific

Paula's Choice Clinical Niacinamide 20% Treatment vs Principia Mix-01 5% Niacinamida 4% Ácido Glicólico 3% Ácido Tranexâmico 2% Ácido Salicílico

Comparing Paula's Choice Clinical Niacinamide 20% Treatment versus Principia Mix-01 5% Niacinamida 4% Ácido Glicólico 3% Ácido Tranexâmico 2% Ácido Salicílico — shared ingredients, unique components, comedogenic & irritancy ratings and unique benefits.

Comparison Overview

Clinical Niacinamide 20% Treatment

Product 1

Paula's Choice Clinical Niacinamide 20% Treatment

vs
Mix-01 5% Niacinamida 4% Ácido Glicólico 3% Ácido Tranexâmico 2% Ácido Salicílico

Product 2

Principia Mix-01 5% Niacinamida 4% Ácido Glicólico 3% Ácido Tranexâmico 2% Ácido Salicílico

4

Shared Ingredients

21

Unique to Paula's Choice Clinical Niacinamide 20% Treatment

11

Unique to Principia Mix-01 5% Niacinamida 4% Ácido Glicólico 3% Ácido Tranexâmico 2% Ácido Salicílico

Neither product contains highly comedogenic ingredients (rating ≥ 3), making both suitable for acne-prone skin. Paula's Choice Clinical Niacinamide 20% Treatment scores lower on irritancy, which may suit sensitive skin better. Both products share 4 ingredients in common. Paula's Choice Clinical Niacinamide 20% Treatment has 21 unique ingredients while Principia Mix-01 5% Niacinamida 4% Ácido Glicólico 3% Ácido Tranexâmico 2% Ácido Salicílico has 11.

Skin Safety Profile

Product Benefits & Effects

✓Positive — Beneficial effects !Caution — Monitor closely

Clinical Niacinamide 20% Treatment Benefits

!May Worsen Eczema✓Good For Oily Skin✓Acne Fighting✓Has Anti-aging properties✓Improves skin texture✓Has skin-brightening properties✓Reduces dark spots✓Redness Reducing✓Reduces Irritation

Mix-01 5% Niacinamida 4% Ácido Glicólico 3% Ácido Tranexâmico 2% Ácido Salicílico Benefits

!May Worsen Eczema✓Good For Oily Skin✓Acne Fighting✓Improves skin texture✓Has Anti-aging properties✓Has skin-brightening properties!May cause dryness for some skin types✓Reduces dark spots!May cause irritation for some skin types✓Redness Reducing!May Worsen Rosacea✓Reduces Large Pores

Ingredient Analysis Matrix

⇄ Swap Positions
Scale 1 2 3 4 5 low → high
C = Comedogenic S = Safety risk IR = Irritancy
1

Ingredients — Unique to Paula's Choice Clinical Niacinamide 20% Treatment

Pentylene GlycolCSIRButylene GlycolCSIRGlycerinCSIRAcetyl GlucosamineCSIRAscorbyl GlucosideCSIRGlycyrrhiza Glabra Root ExtractCSIRSpiraea Ulmaria ExtractCSIRPortulaca Oleracea ExtractCSIRCamellia Japonica Flower ExtractCSIREpigallocatechin GallateCSIRBoerhavia Diffusa Root ExtractCSIRCamellia Sinensis Leaf ExtractCSIRAllantoinCSIRLecithinCSIRPullulanCSIRPanthenolCSIRSilicaCSIRSclerotium GumCSIRSodium PhytateCSIRPhenoxyethanolCSIREthylhexylglycerinCSIR
2

Ingredients — Unique to Principia Mix-01 5% Niacinamida 4% Ácido Glicólico 3% Ácido Tranexâmico 2% Ácido Salicílico

EthoxydiglycolCSIRSodium HyaluronateCSIRSodium HydroxideCSIRTranexamic AcidCSIRCitric AcidCSIRGlycolic AcidCSIRSalicylic AcidCSIRBenzyl AlcoholCSIRBenzoic AcidCSIRDehydroacetic AcidCSIRAlcoholCSIR

Frequently Asked Questions

Is Paula's Choice Clinical Niacinamide 20% Treatment better than Principia Mix-01 5% Niacinamida 4% Ácido Glicólico 3% Ácido Tranexâmico 2% Ácido Salicílico for sensitive skin?

By comparing Clinical Niacinamide 20% Treatment and Mix-01 5% Niacinamida 4% Ácido Glicólico 3% Ácido Tranexâmico 2% Ácido Salicílico side-by-side, you can identify which product has fewer irritants and a better safety profile for sensitive skin. Check the irritancy ratings in the comparison matrix above.

Which product, Clinical Niacinamide 20% Treatment or Mix-01 5% Niacinamida 4% Ácido Glicólico 3% Ácido Tranexâmico 2% Ácido Salicílico, is safer for acne-prone skin?

The comparison tool highlights comedogenic (pore-clogging) ingredients in both Clinical Niacinamide 20% Treatment and Mix-01 5% Niacinamida 4% Ácido Glicólico 3% Ácido Tranexâmico 2% Ácido Salicílico. Review the comedogenic ratings above to see which formulation is less likely to cause breakouts.

Do Clinical Niacinamide 20% Treatment and Mix-01 5% Niacinamida 4% Ácido Glicólico 3% Ácido Tranexâmico 2% Ácido Salicílico share any ingredients?

Our ingredient analysis matrix lists all shared ingredients as well as those unique to either Clinical Niacinamide 20% Treatment or Mix-01 5% Niacinamida 4% Ácido Glicólico 3% Ácido Tranexâmico 2% Ácido Salicílico.

Popular Skincare Comparisons

CeraVe Hydrating Facial Cleanser vs La Roche-Posay Toleriane Hydrating Gentle Face Cleanser

Compare

The Ordinary Niacinamide 10% + Zinc 1% vs The Inkey List Niacinamide Serum

Compare

Laneige Water Bank Blue Hyaluronic Cream vs Tatcha The Water Cream

Compare

Paula's Choice Skin Perfecting 2% BHA vs Drunk Elephant T.L.C. Framboos Glycolic Serum

Compare

Cosrx Advanced Snail 96 Mucin Power Essence vs Beauty of Joseon Repair Serum

Compare

Beauty of Joseon Relief Sun Rice & Probiotics vs Isntree Hyaluronic Acid Watery Sun Gel SPF50+

Compare