5 in 1 Retinol, Vitamin C, Collagen, Hyaluronic Acid and Niacinamide | Potent Face Cream which May Help Improve Appearance of Fine Lines and Wrinkles and Reduce Appearance of Dark Spots

Updated on: 06/04/2025

Total Ingredients

analysed

20 of 32

Skin-Safe

low risk

3 of 32

Potential Irritants

may irritate sensitive skin

0 of 32

Potential Pore-Clogging

comedogenic risk

About this product

32 ingredients

3 potential irritant

none pore-clogging

Contains Niacinamide and Retinol. Contains fragrance — patch test if sensitive. Formula aimed at oily and acne-prone skin. Patch-test if you have very reactive skin.

Formulation Analysis

Click any ingredient to view full details

C: Comedogenic·S: Safety·Ir: Irritancy

1 Very safe

2 Safe

3 Moderate

4 Risky

5 Avoid

C: Comedogenic·S: Safety·Ir: Irritancy

1 Very safe

2 Safe

3 Moderate

4 Risky

5 Avoid

Water

Comedogenic: Very low risk

Safety: Very low risk

Irritancy: Very low risk

Plaque Prevention Agent Skin Enhancer Ingredient Dissolver

Carthamus Tinctorius Seed Oil

Comedogenic: Very low risk

Safety: Very low risk

Irritancy: Very low risk

Skin Enhancer Scent Provider

Cyclopentasiloxane

Comedogenic: Very low risk

Safety: Low risk

Irritancy: Very low risk

Skin Enhancer Ingredient Dissolver Hair Softener +1

Cetearyl Alcohol

Comedogenic: Low risk

Safety: Very low risk

Irritancy: Low risk

Cloudiness Creator Foam Enhancer Cleansing Surfactant +4

Polysorbate 60

Comedogenic: Low risk

Safety: Low risk

Irritancy: Low risk

Cleansing Surfactant Emulsifying Surfactant

Dimethicone

Comedogenic: Very low risk

Safety: Very low risk

Irritancy: Very low risk

Skin Enhancer Skin Softener Defensive Shield +1

Niacinamide

Comedogenic: Very low risk

Safety: Very low risk

Irritancy: Low risk

Surface Refiner

Sodium Hyaluronate

Comedogenic: Very low risk

Safety: Very low risk

Irritancy: Very low risk

Skin Enhancer Moisture Magnet

Retinyl Palmitate

Comedogenic: Low risk

Safety: Moderate risk

Irritancy: Moderate risk

General Skin Improver

Ascorbic Acid

Comedogenic: Very low risk

Safety: Low risk

Irritancy: Moderate risk

Anti-Aging Protector Skin Enhancer pH Stabilizer +1

Retinol

Comedogenic: Very low risk

Safety: Moderate risk

Irritancy: High risk

General Skin Improver

Tocopherol

Comedogenic: Low risk

Safety: Low risk

Irritancy: Low risk

General Skin Improver Moisture Barrier Creator Anti-Aging Protector +1

Carnitine

Safety: Very low risk

Irritancy: Very low risk

Foam Enhancer Cleansing Surfactant Skin Enhancer +4

Glycerin

Comedogenic: Very low risk

Safety: Very low risk

Irritancy: Very low risk

Fragrance Provider Moisture Magnet Thickness Regulator +7

Chamomilla Recutita Flower Extract

Safety: Low risk

Irritancy: Low risk

Skin Enhancer Scent Provider

Citrus Aurantium Dulcis Flower Extract

Safety: Moderate risk

Irritancy: Moderate risk

Skin Enhancer

Salvia Officinalis Leaf Extract

Safety: Low risk

Irritancy: Low risk

Scalp Condition Treatment Skin Enhancer Revitalizer +2

Citrus Aurantium Bergamia Fruit Extract

Safety: Moderate risk

Irritancy: Moderate risk

Skin Enhancer

Vitis Vinifera Seed Oil

Comedogenic: Very low risk

Safety: Very low risk

Irritancy: Very low risk

Skin Enhancer Skin Softener

Saccharomyces/Copper Ferment

Skin Enhancer

Dimethylaminoethanol Tartrate

Safety: Moderate risk

Irritancy: Moderate risk

Skin Enhancer Skin Softener

Thioctic Acid

Safety: Low risk

Irritancy: Moderate risk

Anti-Aging Protector

Ubiquinone

Safety: Very low risk

Irritancy: Very low risk

Anti-Aging Protector Skin Enhancer

Phenoxyethanol

Safety: Low risk

Irritancy: Moderate risk

Product Protector Germ Fighter

Ethylhexylglycerin

Comedogenic: Very low risk

Safety: Low risk

Irritancy: Low risk

Skin Enhancer Odor Neutralizer

Parfum

Safety: Moderate risk

Irritancy: High risk

Fragrance Provider Scent Provider

Ci 19140

Safety: Moderate risk

Hair Color Changer Color Provider

Collagen

Safety: Low risk

Skin Enhancer Skin Hydrator Hair Softener

Eugenia Caryophyllus Bud Oil

Safety: High risk

Irritancy: High risk

Fragrance Provider Scent Provider

Cream

Skin Enhancer Skin Softener

Vitamin C

Vitamin E

Ingredient Name	Safety Profile	Functionality
01 Water	C 1 Comedogenic: Very low risk S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Plaque Prevention Agent Skin Enhancer +1
02 Carthamus Tinctorius Seed Oil	C 1 Comedogenic: Very low risk S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Skin Enhancer Scent Provider
03 Cyclopentasiloxane	C 1 Comedogenic: Very low risk S 2 Safety: Low risk Ir 1 Irritancy: Very low risk	Skin Enhancer Ingredient Dissolver +2
04 Cetearyl Alcohol	C 2 Comedogenic: Low risk S 1 Safety: Very low risk Ir 2 Irritancy: Low risk	Cloudiness Creator Foam Enhancer +5
05 Polysorbate 60	C 2 Comedogenic: Low risk S 2 Safety: Low risk Ir 2 Irritancy: Low risk	Cleansing Surfactant Emulsifying Surfactant
06 Dimethicone	C 1 Comedogenic: Very low risk S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Skin Enhancer Skin Softener +2
07 Niacinamide	C 1 Comedogenic: Very low risk S 1 Safety: Very low risk Ir 2 Irritancy: Low risk	Surface Refiner
08 Sodium Hyaluronate	C 1 Comedogenic: Very low risk S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Skin Enhancer Moisture Magnet
09 Retinyl Palmitate	C 2 Comedogenic: Low risk S 3 Safety: Moderate risk Ir 3 Irritancy: Moderate risk	General Skin Improver
10 Ascorbic Acid	C 1 Comedogenic: Very low risk S 2 Safety: Low risk Ir 3 Irritancy: Moderate risk	Anti-Aging Protector Skin Enhancer +2
11 Retinol	C 1 Comedogenic: Very low risk S 3 Safety: Moderate risk Ir 4 Irritancy: High risk	General Skin Improver
12 Tocopherol	C 2 Comedogenic: Low risk S 2 Safety: Low risk Ir 2 Irritancy: Low risk	General Skin Improver Moisture Barrier Creator +2
13 Carnitine	S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Foam Enhancer Cleansing Surfactant +5
14 Glycerin	C 1 Comedogenic: Very low risk S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Fragrance Provider Moisture Magnet +8
15 Chamomilla Recutita Flower Extract	S 2 Safety: Low risk Ir 2 Irritancy: Low risk	Skin Enhancer Scent Provider
16 Citrus Aurantium Dulcis Flower Extract	S 3 Safety: Moderate risk Ir 3 Irritancy: Moderate risk	Skin Enhancer
17 Salvia Officinalis Leaf Extract	S 2 Safety: Low risk Ir 2 Irritancy: Low risk	Scalp Condition Treatment Skin Enhancer +3
18 Citrus Aurantium Bergamia Fruit Extract	S 3 Safety: Moderate risk Ir 3 Irritancy: Moderate risk	Skin Enhancer
19 Vitis Vinifera Seed Oil	C 1 Comedogenic: Very low risk S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Skin Enhancer Skin Softener
20 Saccharomyces/Copper Ferment		Skin Enhancer
21 Dimethylaminoethanol Tartrate	S 3 Safety: Moderate risk Ir 3 Irritancy: Moderate risk	Skin Enhancer Skin Softener
22 Thioctic Acid	S 2 Safety: Low risk Ir 3 Irritancy: Moderate risk	Anti-Aging Protector
23 Ubiquinone	S 1 Safety: Very low risk Ir 1 Irritancy: Very low risk	Anti-Aging Protector Skin Enhancer
24 Phenoxyethanol	S 2 Safety: Low risk Ir 3 Irritancy: Moderate risk	Product Protector Germ Fighter
25 Ethylhexylglycerin	C 1 Comedogenic: Very low risk S 2 Safety: Low risk Ir 2 Irritancy: Low risk	Skin Enhancer Odor Neutralizer
26 Parfum	S 3 Safety: Moderate risk Ir 4 Irritancy: High risk	Fragrance Provider Scent Provider
27 Ci 19140	S 3 Safety: Moderate risk	Hair Color Changer Color Provider
28 Collagen	S 2 Safety: Low risk	Skin Enhancer Skin Hydrator +1
29 Eugenia Caryophyllus Bud Oil	S 4 Safety: High risk Ir 4 Irritancy: High risk	Fragrance Provider Scent Provider
30 Cream		Skin Enhancer Skin Softener
31 Vitamin C		N/A
32 Vitamin E		N/A

Potential Irritants

3 flagged

Citrus Aurantium Dulcis Flower Extract Citrus Aurantium Bergamia Fruit Extract Parfum

Community

Dermedicine 5 in 1 Retinol, Vitamin C, Collagen, Hyaluronic Acid and Niacinamide | Potent Face Cream which May Help Improve Appearance of Fine Lines and Wrinkles and Reduce Appearance of Dark Spots Reviews

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Common Questions

Frequently Asked Questions

Is Dermedicine 5 in 1 Retinol, Vitamin C, Collagen, Hyaluronic Acid and Niacinamide | Potent Face Cream which May Help Improve Appearance of Fine Lines and Wrinkles and Reduce Appearance of Dark Spots comedogenic?

Appears Non-Comedogenic 5 in 1 Retinol, Vitamin C, Collagen, Hyaluronic Acid and Niacinamide | Potent Face Cream which May Help Improve Appearance of Fine Lines and Wrinkles and Reduce Appearance of Dark Spots appears to be non-comedogenic based on our ingredient analysis. None of its 32 ingredients carry a high comedogenic rating, making it generally suitable for acne-prone and oily skin types.

Is Dermedicine a good skincare brand?

Dermedicine makes products such as 5 in 1 Retinol, Vitamin C, Collagen, Hyaluronic Acid and Niacinamide | Potent Face Cream which May Help Improve Appearance of Fine Lines and Wrinkles and Reduce Appearance of Dark Spots that include some ingredients which may be problematic for sensitive or acne-prone skin. Check individual product ingredient lists and community reviews before deciding. Read more about Dermedicine.

Use with Caution 5 in 1 Retinol, Vitamin C, Collagen, Hyaluronic Acid and Niacinamide | Potent Face Cream which May Help Improve Appearance of Fine Lines and Wrinkles and Reduce Appearance of Dark Spots may not be ideal for sensitive skin. It contains 5 potential irritant s including <a href="/ingredient/retinol" class="font-bold underline hover:text-cyan-700">Retinol</a>, <a href="/ingredient/parfum" class="font-bold underline hover:text-cyan-700">Parfum</a> and <a href="/ingredient/eugenia-caryophyllus-bud-oil" class="font-bold underline hover:text-cyan-700">Eugenia Caryophyllus Bud Oil</a> . Common triggers like Fragrance, Limonene, and Linalool can cause redness or reactions in sensitive or barrier-compromised skin. We recommend patch testing before full use.

Does Dermedicine 5 in 1 Retinol, Vitamin C, Collagen, Hyaluronic Acid and Niacinamide | Potent Face Cream which May Help Improve Appearance of Fine Lines and Wrinkles and Reduce Appearance of Dark Spots clog pores?

Unlikely to Clog Pores Based on our analysis, 5 in 1 Retinol, Vitamin C, Collagen, Hyaluronic Acid and Niacinamide | Potent Face Cream which May Help Improve Appearance of Fine Lines and Wrinkles and Reduce Appearance of Dark Spots is unlikely to clog pores. None of its 32 ingredients have a comedogenic rating above 2.

Who makes Dermedicine 5 in 1 Retinol, Vitamin C, Collagen, Hyaluronic Acid and Niacinamide | Potent Face Cream which May Help Improve Appearance of Fine Lines and Wrinkles and Reduce Appearance of Dark Spots?

This product is from Dermedicine. See more products from Dermedicine.

What are the ingredients in Dermedicine 5 in 1 Retinol, Vitamin C, Collagen, Hyaluronic Acid and Niacinamide | Potent Face Cream which May Help Improve Appearance of Fine Lines and Wrinkles and Reduce Appearance of Dark Spots?

5 in 1 Retinol, Vitamin C, Collagen, Hyaluronic Acid and Niacinamide | Potent Face Cream which May Help Improve Appearance of Fine Lines and Wrinkles and Reduce Appearance of Dark Spots contains 32 ingredients. The first ingredients listed are <a href="/ingredient/water" class="font-bold underline hover:text-cyan-700">Water</a>, <a href="/ingredient/carthamus-tinctorius-seed-oil" class="font-bold underline hover:text-cyan-700">Carthamus Tinctorius Seed Oil</a>, <a href="/ingredient/cyclopentasiloxane" class="font-bold underline hover:text-cyan-700">Cyclopentasiloxane</a>, <a href="/ingredient/cetearyl-alcohol" class="font-bold underline hover:text-cyan-700">Cetearyl Alcohol</a> and <a href="/ingredient/polysorbate-60" class="font-bold underline hover:text-cyan-700">Polysorbate 60</a>. Each ingredient includes a comedogenic rating, irritancy rating, and safety score. View the full annotated ingredient list above.

What do users say about Dermedicine 5 in 1 Retinol, Vitamin C, Collagen, Hyaluronic Acid and Niacinamide | Potent Face Cream which May Help Improve Appearance of Fine Lines and Wrinkles and Reduce Appearance of Dark Spots?

No Reviews Yet 5 in 1 Retinol, Vitamin C, Collagen, Hyaluronic Acid and Niacinamide | Potent Face Cream which May Help Improve Appearance of Fine Lines and Wrinkles and Reduce Appearance of Dark Spots does not yet have community reviews on SkinWis. Be the first to share your experience.

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