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Total Defense + Repair + SPF 50

Updated on: 10/05/2025
Total Defense + Repair + SPF 50
45
Total Ingredients
analysed
36 of 45
Skin-Safe
low risk
0 of 45
Potential Irritants
may irritate sensitive skin
0 of 45
Potential Pore-Clogging
+2 moderate pore-clogging

Product Analysis Summary

About this product

Contains Niacinamide and Vitamin C. Mostly fragrance‑free. Formula aimed at skin types that tolerate moderate comedogenic ingredients. Patch-test if you have very reactive skin.

Formulation Analysis

Click any ingredient to view full details

C: Comedogenic·S: Safety·Ir: Irritancy
1 Very safe
2 Safe
3 Moderate
4 Risky
5 Avoid
S
3
Safety: Moderate risk
Ir
3
Irritancy: Moderate risk
C
2
Comedogenic: Low risk
S
3
Safety: Moderate risk
Ir
3
Irritancy: Moderate risk
C
1
Comedogenic: Very low risk
S
1
Safety: Very low risk
Ir
1
Irritancy: Very low risk
C
2
Comedogenic: Low risk
S
2
Safety: Low risk
Ir
2
Irritancy: Low risk
C
1
Comedogenic: Very low risk
S
1
Safety: Very low risk
Ir
1
Irritancy: Very low risk
C
1
Comedogenic: Very low risk
S
1
Safety: Very low risk
Ir
1
Irritancy: Very low risk
C
1
Comedogenic: Very low risk
S
1
Safety: Very low risk
Ir
1
Irritancy: Very low risk
C
1
Comedogenic: Very low risk
S
1
Safety: Very low risk
Ir
2
Irritancy: Low risk
C
1
Comedogenic: Very low risk
S
2
Safety: Low risk
Ir
2
Irritancy: Low risk
C
3
Comedogenic: Moderate risk
S
2
Safety: Low risk
Ir
1
Irritancy: Very low risk
C
2
Comedogenic: Low risk
S
2
Safety: Low risk
Ir
2
Irritancy: Low risk
C
2
Comedogenic: Low risk
S
1
Safety: Very low risk
Ir
2
Irritancy: Low risk
C
1
Comedogenic: Very low risk
S
1
Safety: Very low risk
Ir
1
Irritancy: Very low risk
S
2
Safety: Low risk
Ir
2
Irritancy: Low risk
S
2
Safety: Low risk
Ir
1
Irritancy: Very low risk
S
1
Safety: Very low risk
Ir
1
Irritancy: Very low risk
C
1
Comedogenic: Very low risk
S
1
Safety: Very low risk
Ir
1
Irritancy: Very low risk
C
1
Comedogenic: Very low risk
S
1
Safety: Very low risk
Ir
1
Irritancy: Very low risk
S
2
Safety: Low risk
C
2
Comedogenic: Low risk
S
1
Safety: Very low risk
Ir
2
Irritancy: Low risk
S
2
Safety: Low risk
Ir
1
Irritancy: Very low risk
C
2
Comedogenic: Low risk
S
1
Safety: Very low risk
Ir
1
Irritancy: Very low risk
C
1
Comedogenic: Very low risk
S
1
Safety: Very low risk
Ir
2
Irritancy: Low risk
C
3
Comedogenic: Moderate risk
S
2
Safety: Low risk
Ir
2
Irritancy: Low risk
C
1
Comedogenic: Very low risk
S
1
Safety: Very low risk
Ir
1
Irritancy: Very low risk
C
1
Comedogenic: Very low risk
S
2
Safety: Low risk
Ir
2
Irritancy: Low risk
S
2
Safety: Low risk
Ir
1
Irritancy: Very low risk
C
1
Comedogenic: Very low risk
S
2
Safety: Low risk
Ir
2
Irritancy: Low risk
S
2
Safety: Low risk
Ir
2
Irritancy: Low risk
S
2
Safety: Low risk
Ir
3
Irritancy: Moderate risk

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Common Questions

Frequently Asked Questions

Is SkinMedica Total Defense + Repair + SPF 50 comedogenic?

Mixed Profile — Patch Test Advised Total Defense + Repair + SPF 50 has a mixed comedogenic profile. It contains 2 ingredient s with a moderate comedogenic rating (3) that could potentially clog pores for some skin types. Those with acne-prone skin should patch test first.

Is SkinMedica a good skincare brand?

SkinMedica is a US clinical skincare brand founded in 1999. It is known for physician‑developed anti‑aging and corrective formulations, including TNS Essential Serum, growth factor serums, and retinol products. Assess products individually by reviewing their ingredient lists and community feedback. Read more about SkinMedica.

Is SkinMedica Total Defense + Repair + SPF 50 safe for sensitive skin?

Appears Suitable for Sensitive Skin Total Defense + Repair + SPF 50 appears suitable for sensitive skin based on its ingredient profile. No common irritants detected among its 45 ingredients. Always patch test when trying a new product.

Does SkinMedica Total Defense + Repair + SPF 50 clog pores?

Potential Pore-Cloggers Present Total Defense + Repair + SPF 50 contains 2 ingredients with a comedogenic rating of 3 or higher that may clog pores , including <a href="/ingredient/glyceryl-stearate" class="font-bold underline hover:text-cyan-700">Glyceryl Stearate</a> and <a href="/ingredient/isostearic-acid" class="font-bold underline hover:text-cyan-700">Isostearic Acid</a> . Every ingredient's comedogenic rating is listed above.

Who makes SkinMedica Total Defense + Repair + SPF 50?

This product is from SkinMedica. See more products from SkinMedica.

What are the ingredients in SkinMedica Total Defense + Repair + SPF 50?

Total Defense + Repair + SPF 50 contains 45 ingredients. The first ingredients listed are <a href="/ingredient/homosalate" class="font-bold underline hover:text-cyan-700">Homosalate</a>, <a href="/ingredient/ethylhexyl-methoxycinnamate" class="font-bold underline hover:text-cyan-700">Ethylhexyl Methoxycinnamate</a>, <a href="/ingredient/ethylhexyl-salicylate" class="font-bold underline hover:text-cyan-700">Ethylhexyl Salicylate</a>, <a href="/ingredient/camellia-sinensis-extract" class="font-bold underline hover:text-cyan-700">Camellia Sinensis Extract</a> and <a href="/ingredient/unspecified-form-of-vitamin-c" class="font-bold underline hover:text-cyan-700">Unspecified form of vitamin c</a>. Each ingredient includes a comedogenic rating, irritancy rating, and safety score. View the full annotated ingredient list above.

What do users say about SkinMedica Total Defense + Repair + SPF 50?

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Cross-Reference Data

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